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Itraconazole-induced thrombocytopenia

Cutaneous and Ocular Toxicology, 2016
Itraconazole is one of the systemic treatment options for extensive tinea versicolor. A male patient who developed thrombocytopenia during the treatment of tinea versicolor by itraconazole is reported in this manuscript. He was diagnosed to develop thrombocytopenia on the third day of treatment.
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Resistance of Aspergillus fumigatus to Itraconazole

Scandinavian Journal of Infectious Diseases, 1998
ment with the drug. The author concluded that the A. fumigatus strains acquired resistance to itraconazole during or following treatment. The author, however, failed to determine whether or not the isolates cultured from the sputa were genotypically identical. Although invasive infections by Aspergillus species are generally caused by a single genotype
Verweij, P.E., Voss, A., Meis, J.F.G.M.
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Itraconazole in Pityriasis Versicolor

Clinical Infectious Diseases, 1987
Forty-two patients with pityriasis versicolor were treated with itraconazole. Patients were allocated randomly to one of two groups; the first group (22 patients) received 200 mg of itraconazole per day for five days, and the second group (20 patients) received 100 mg per day for the same period. The study lasted 30 days.
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Itraconazole and flucytosine+itraconazole combination in the treatment of experimental cryptococcosis in hamsters

Mycoses, 1995
Summary. The efficacy of two different daily doses of itraconazole (ITRA) and the combination of flucytosine (5‐FC) with ITRA in the treatment of an experimental model of cryptococcosis in hamsters was studied. Five groups of 20 animals each were inoculated by the intracardiac route with 105 cells of Cryptococcus neoformans.
J. L. Finquelievich   +4 more
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Itraconazole in Human Histoplasmosis: Itraconazol bei Histoplasmose des Menschen

Mycoses, 1989
Summary:A non‐comparative open trial with itraconazole in progressive forms of human histoplasmosis was carried out. Thirty two patients who completed 6 months of treatment were included; 29 suffered the chronic disseminated form; 2 exhibited a chronic pulmonary histoplasmosis and one patient presented a subacute disseminated form. Thirty patients were
A. M. Robles   +3 more
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Effect of omeprazole on the pharmacokinetics of itraconazole

European Journal of Clinical Pharmacology, 1998
To investigate the effect of omeprazole on the pharmacokinetics of itraconazole.Eleven healthy volunteers received a single dose of oral itraconazole (200 mg) on days 1 and 15 and oral omeprazole (40 mg) once daily from day 2 to day 15. Itraconazole pharmacokinetics were studied on days 1 and 15.Concentrations of itraconazole were higher when it was ...
Somchai Sriwiriyajan   +1 more
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Pulmonary Sporotrichosis Treated With Itraconazole

Chest, 1993
A 62-year-old woman had chronic cavitary pulmonary sporotrichosis refractory to medical management over an 8-year period. She was treated with oral itraconazole and had an apparent microbiologic and clinical response; however, the patient succumbed to progressive pulmonary hypertension.
James L. Breeling, Louis Weinstein
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The many lives of itraconazole

Expert Opinion on Therapeutic Patents, 2003
Since the discovery of the highly potent antifungal itraconazole (Sporanox®, Janssen Pharmaceutica) in the late 1970s, numerous patent applications and issued patents have appeared that describe and claim improvements for methods, manufacturing processes, formulations, enantiomers and uses for this commercially successful antifungal agent.
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Itraconazole-Digoxin Interaction

Annals of Internal Medicine, 1992
Excerpt To the Editors: Itraconazole, a triazole derivative of ketoconazole, has shown substantial promise as therapy for fungal infections (1).
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Desensitization to itraconazole

Journal of Allergy and Clinical Immunology, 1997
Robyn E O'Hehir   +3 more
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