Results 11 to 20 of about 25,211 (209)

iQuantitator: A tool for protein expression inference using iTRAQ [PDF]

BMC Bioinformatics, 2009
Background Isobaric Tags for Relative and Absolute Quantitation (iTRAQ™) [Applied Biosystems] have seen increased application in differential protein expression analysis.
Comte-Walters Susana, Krug Edward L, Hill Elizabeth G, Schwacke John H, Schey Kevin L   +4 more
doaj   +3 more sources

Multiplex analysis of sphingolipids using amine-reactive tags (iTRAQ) [PDF]

Journal of Lipid Research, 2011
Ceramides play a crucial role in divergent signaling events, including differentiation, senescence, proliferation, and apoptosis. Ceramides are a minor lipid component in terms of content; thus, highly sensitive detection is required for accurate ...
Takuji Nabetani, Asami Makino, Françoise Hullin-Matsuda, Taka-aki Hirakawa, Shinji Takeoka, Nozomu Okino, Makoto Ito, Toshihide Kobayashi, Yoshio Hirabayashi   +8 more
doaj   +3 more sources

Overexpression of Transferrin Receptor in Esophageal Squamous Cell Cancer Suggests Poor Prognosis and Potential Therapy. [PDF]

Cancer Sci
This study aimed to evaluate transferrin receptor (TfR) expression in human esophageal squamous cell cancer (ESCC) specimens and investigate the correlation between TfR overexpression and clinicopathological characteristics. Furthermore, we explored the potential of targeting iron metabolism pathways as a novel therapeutic strategy for ESCC.
Ikenaga N, Takahashi T, Tanaka K, Serada S, Fujimoto M, Momose K, Yamashita K, Makino T, Saito T, Yamamoto K, Kurokawa Y, Nakajima K, Fujii T, Morii E, Naka T, Eguchi H, Doki Y.   +16 more
europepmc   +2 more sources

i-Tracker: For quantitative proteomics using iTRAQ™ [PDF]

BMC Genomics, 2005
Abstract Background iTRAQ™ technology for protein quantitation using mass spectrometry is a recent, powerful means of determining relative protein levels in up to four samples simultaneously. Although protein identification of samples generated using iTRAQ may be carried out using any current identification software ...
Shadforth, IP, Dunkley, TPJ, Lilley, KS, Bessant, C   +3 more
openaire   +3 more sources

iTRAQ-Based Shotgun Neuroproteomics [PDF]

, 2009
Shotgun proteomics involves the analysis of peptides obtained by enzymatic digestions of proteins and subsequent identification via tandem mass spectrometry. This approach is an effective method for studying global protein expression in neuronal systems.
Tong, Liu, Jun, Hu, Hong, Li
openaire   +2 more sources

A Statistical Model for iTRAQ Data Analysis [PDF]

Journal of Proteome Research, 2008
We describe biological and experimental factors that induce variability in reporter ion peak areas obtained from iTRAQ experiments. We demonstrate how these factors can be incorporated into a statistical model for use in evaluating differential protein expression and highlight the benefits of using analysis of variance to quantify fold change.
Elizabeth G, Hill, John H, Schwacke, Susana, Comte-Walters, Elizabeth H, Slate, Ann L, Oberg, Jeanette E, Eckel-Passow, Terry M, Therneau, Kevin L, Schey   +7 more
openaire   +2 more sources

The isobaric tags for relative and absolute quantification-based quantitative proteomics of fresh tissue-derived secretome in hepatocellular carcinoma

Archives of Medical Science, 2021
Introduction Proteomics technology platforms offer an extremely useful tool for the discovery of new cancer biomarkers. Secreted proteins play important roles in signal transduction, cellular growth, proliferation, differentiation, and apoptosis.
Hai-Tao Jiang, Guo-Sheng Gao, Feng Ren, Yun-Jie Chen   +3 more
doaj   +1 more source

Comparative transcriptome and proteome analysis of lily clones inoculated with Fusarium oxysporum f. sp. lilii

Ornamental Plant Research, 2022
Basal bulb rot is the major factor restricting the production of lily, caused by Fusarium oxysporum f. sp. lilii. To systematically analyze the transcriptomic and proteomic responses of lily clones to F.
Yiping Zhang, Xin Wang, Chunlian Jin, Feng Xu, Xiumei Yang, Yalian Jiang, Lifang Zhang, Lihua Wang, Yan Su, Lulin Ma, Jihua Wang   +10 more
doaj   +1 more source

Proteomic analysis provides integrated insight into mechanisms of Turnip mosaic virus long distance movement in Brassica rapa

Biologia Plantarum, 2019
In non-heading Chinese cabbage, the yield relies mostly on the health of leaves, which can be heavily impacted by turnip mosaic virus (TuMV). The virions or viral ribonucleoprotein complexes are transported through the phloem and xylem. Plasmodesmata are
C. Liu, G.-S. Sun, R.-J. Zhang, S.-W. Lv, L. Gao, L.-W. Gao, T.-K. Liu, D. Xiao, X.-L. Hou, C.-W. Zhang   +9 more
doaj   +1 more source

Translocation of Drought-Responsive Proteins from the Chloroplasts

Cells, 2020
Some chloroplast proteins are known to serve as messengers to transmit retrograde signals from chloroplasts to the nuclei in response to environmental stresses.
Ping Li, Haoju Liu, Hong Yang, Xiaojun Pu, Chuanhong Li, Heqiang Huo, Zhaohui Chu, Yuxiao Chang, Yongjun Lin, Li Liu   +9 more
doaj   +1 more source