Results 61 to 70 of about 24,385 (266)

The Homozygous p.(Arg215Ter) Variant in XRCC2 Is Associated With Atypical Fanconi Anemia Without Major Hematological Abnormalities in Childhood

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Fanconi Anemia (FA) is the most frequent inherited bone marrow failure syndrome. A role for the XRCC2 gene in FA was suspected in 2012 and confirmed in 2016, but only two affected individuals have been described thus far, and no long‐term follow‐up is available.
Sabina Cenciarelli, Giulia Bruna Marchetti, Maria Iascone, Maria Grazia Patricelli, Sara Giangiobbe, Gabriella Cinzia Pozzobon, Miriam Nella Savini, Fabio Giglio, Alessandro Aiuti, Paola Carrera, Francesca Ferrua, Angela Peron   +11 more
wiley   +1 more source

Use of sildenafil citrate in cases of intrauterine growth restriction (IUGR); a prospective trial.

Taiwanese Journal of Obstetrics & Gynecology, 2018
OBJECTIVE Intrauterine growth restriction (IUGR) is one of the most serious complications of pregnancy. Up to date, there is no evidence of achieving antenatal treatment of IUGR with abnormal placentation. Although, Sildenafil citrate has shown promising
Mohammed Maged, A. Wageh, M. Shams, Abdlgawad Elmetwally   +3 more
semanticscholar   +1 more source

Normal Placental Development and the Triad of Placental Dysfunction: The Maternal and Fetal Complications

Journal of Contemporary Medicine, 2019
The placenta is crucial to the development of a fetus, playing a vital role from fertilization of an egg by sperm until the delivery of the fetus. Without the placenta, the fetus would not receive essential nutrients or oxygen from the mother and be able
Sathees B Chandra, Arielle Hough
doaj   +1 more source

Body composition and organ development of intra-uterine growth restricted pigs at weaning

Animal, 2020
Sow litter sizes have increased, subjecting more small piglets to intra-uterine growth restriction (IUGR). Research on the development and growth of IUGR pigs is limited.
J.C. Lynegaard, C.F. Hansen, A.R. Kristensen, C. Amdi   +3 more
doaj   +1 more source

Dietary N-carbamylglutamate and L-arginine supplementation improves redox status and suppresses apoptosis in the colon of intrauterine growth-retarded suckling lambs

Animal Nutrition, 2022
Previous studies have revealed that dietary N-carbamylglutamate (NCG) or L-arginine (Arg) improves small intestinal integrity and immune function in suckling Hu lambs that have experienced intrauterine growth retardation (IUGR).
Hao Zhang, Yi Zheng, Xia Zha, Xiaoyun Liu, Yi Ma, Juan J. Loor, Mabrouk Elsabagh, Mengzhi Wang, Hongrong Wang, Honghua Jiang   +9 more
doaj   +1 more source

Spectrum of Congenital Anomalies in Myhre Syndrome—Insights Into Effects Brought by Altered TGF‐β Signaling via Gain‐of‐Function Variants in SMAD4

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is a rare genetic disorder characterized by progressive multisystem involvement. Gain‐of‐function missense heterozygous variants affecting the Ile500 residue and Arg496 residue of the SMAD4 gene are implicated in this condition.
Kawmadi Gunawardena, Alessandro De Falco, Deborah Osio, Eleanor Sherlock, Emma Kivuva, Erina Sasaki, Francis H. Sansbury, Nayana Lahiri, Patricia Foley, Sahar Mansour, Shane McKee, Tazeen Ashraf, Nicola Brunetti‐Pierri, Usha Kini   +13 more
wiley   +1 more source

Myoblast replication is reduced in the IUGR fetus despite maintained proliferative capacity in vitro

Journal of Endocrinology, 2017
Adults who were affected by intrauterine growth restriction (IUGR) suffer from reductions in muscle mass and insulin resistance, suggesting muscle growth may be restricted by molecular events that occur during fetal development.
S. M. Soto, Amy C Blake, Stephanie R. Wesolowski, P. Rozance, Kristen B Barthels, B. Gao, B. Hetrick, C. McCurdy, N. G. Garza, W. Hay, L. Leinwand, J. Friedman, L. Brown   +12 more
semanticscholar   +1 more source

Maternal and neonatal outcomes in Gaza amid armed hostilities in 2025

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study documents facility‐based maternal, obstetric, and neonatal outcomes and associated conflict‐related exposures and living conditions among pregnancy‐related encounters at Al‐Helou Maternity Hospital in Gaza from late April to early September 2025, with a small number of additional encounters recorded at Al‐Shifa Medical ...
Shaymaa Abuhaiba, Younis Elijla, Aya El‐Dadah, Othman Nassar, Meran Abu‐Sultan, Maysaa Almasry, Hebatallah Alkhatib, Mahmoud Alsady, Amir Mahdi Ghafarian, Muath Alsarafandi, Lina Abumughessib, Arham Ali, Yassar Arain, Abeerah Muhammad, Belal Aldabbour, Shayan Ali, Bilal Irfan   +16 more
wiley   +1 more source

Factors associated with height catch-up and catch-down growth among schoolchildren. [PDF]

PLoS ONE, 2012
In developed countries, children with intrauterine growth restriction (IUGR) or born preterm (PT) tend to achieve catch-up growth. There is little information about height catch-up in developing countries and about height catch-down in both developed and
Rosângela F L Batista, Antônio A M Silva, Marco A Barbieri, Vanda M F Simões, Heloisa Bettiol   +4 more
doaj   +1 more source

MicroRNA‐210 level as a biomarker for pre‐eclampsia severity: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Pre‐eclampsia is a serious pregnancy‐related syndrome lacking accurate prognostic markers. MicroRNA‐210, overexpressed in the circulation of women with pre‐eclampsia, has recently emerged as a promising biomarker. Objectives We conducted a systematic review and meta‐analysis to evaluate the relationship between miR‐210 levels and ...
Dávid Márai, Isabel Pinto Amorim das Virgens, Ádám Vincze, Mahmoud Obeidat, Péter Hegyi, Mikolt Bakony, Zsófia Réka Erdélyi, Zsolt Melczer, Sándor Valent   +8 more
wiley   +1 more source