scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu +13 more
wiley +1 more source
Early screening for respiratory and cardiac complications in pediatric mucopolysaccharidosis IVA: Insights from a case. [PDF]
Shu H +5 more
europepmc +1 more source
Using articulating foils of varying thickness, occlusal tactile acuity was compared between patients with chronic painful temporomandibular disorders (TMDp) and healthy controls. TMDp patients showed enhanced detection of thinner foils and greater perceptual sensitivity, accompanied by a more liberal decision strategy, whereas higher frequencies of ...
Iva Z. Alajbeg +5 more
wiley +1 more source
Recent advances in mucopolysaccharidosis IVA treatment. [PDF]
Leal AF, Pachajoa H.
europepmc +1 more source
Abstract Purpose This study evaluated and compared the marginal fidelity of milled zirconia copings before and after finishing and polishing with and without a control die. Materials and Methods This prospective multicenter in vitro trial involved two methods regularly used in two clinics for hybrid and full‐digital workflows.
Marwan Al Akkad +5 more
wiley +1 more source
Practical Considerations for the Diagnosis and Management of Isovaleryl-CoA-Dehydrogenase Deficiency (Isovaleric Acidemia): Systematic Search and Review and Expert Opinions. [PDF]
Thimm E +8 more
europepmc +1 more source
ABSTRACT With over 1000 genetic causes for neurodevelopmental conditions, genetic testing (including exome sequencing) is recommended for people with intellectual disability to guide clinical care, as well as improve empowerment, connection to peer supports, and access to funded therapies.
Manjekah Dunn +9 more
wiley +1 more source
Persistent nasal colonization of rare community-acquired methicillin-resistant <i>Staphylococcus aureus</i> clones ST8-IVl (CA-MRSA/J) and ST1930-IVa in healthy adults. [PDF]
Aung MS +5 more
europepmc +1 more source
Geochemical and petrographic re‐evaluation of ungrouped iron meteorites from Western Australia
Abstract Under the current classification scheme, ungrouped irons make up ~11% of all recognized iron meteorites. A further ~7% of iron meteorites are currently classified as simply “irons” and are yet to be fully classified. To potentially classify these meteorites, newer approaches, including either statistical modeling or advanced geochemical ...
Ashley Rogers +6 more
wiley +1 more source
Implications for cystic fibrosis therapy: Potentiator icenticaftor is superior to ivacaftor in improving function and maintaining stability of F508del CFTR. [PDF]
Cholon DM +6 more
europepmc +1 more source

