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Ivabradine: Cardiovascular Effects
Recent Patents on Cardiovascular Drug Discovery, 2009Ivabradine (a compound of the benzocyclobutane) is a highly selective I(f) current inhibitor acting directly on the sino-atrial node, induces a rapid, sustained and dose-dependent reduction of heart rate at rest and during exercise without a significant effect on atrio-ventricular conduction, left ventricular contraction/relaxation or vascular tissues.
Andrea, Rognoni +3 more
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