Results 201 to 210 of about 48,951 (258)

Ivermectin

open access: yesDermatologic Clinics, 2003
Ivermectin is a potent antiparasitic drug and the first commercially available member of a new class of drugs (macrocyclic lactones) that has been approved for human use. Ivermectin has already proven to be highly effective in the elimination of river blindness as a public health burden.
George W, Elgart, Terri L, Meinking
openaire   +3 more sources

Shortened egg reappearance periods of equine cyathostomins following ivermectin or moxidectin treatment: morphological and molecular investigation of efficacy and species composition.

International Journal of Parasitology, 2022
Macrocyclic lactones (MLs) have been the most widely used drugs for equine parasite control during the past four decades. Unlike ivermectin, moxidectin exhibits efficacy against encysted cyathostomin larvae, and is reported to have persistent efficacy ...
M. K. Nielsen   +8 more
semanticscholar   +1 more source

The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer.

Antiviral Research, 2020
Infection by RNA viruses such as human immunodeficiency virus (HIV)-1, influenza, and dengue virus (DENV) represent a major burden for human health worldwide.
Sundy N. Y. Yang   +6 more
semanticscholar   +1 more source

Pharmacology of ivermectin

Parasitology Today, 1988
Ivermectin is a semi-synthetic macrocyclic lactone (Fig. I) active in single low doses against many parasites - particularly nematodes and arthropods. It has been registered for animal health use since early 1985, and was earlier this year approved for human use by the French Directorate o f Pharmacy and Drugs.
J L, Bennett, J F, Williams, V, Dave
openaire   +2 more sources

Ivermectin and filariasis

Fundamental & Clinical Pharmacology, 2003
AbstractIvermectin, a parasiticide that long ago proved its worth in veterinary medicine, became one of the most effective tools for control programs against human filarial diseases in the 1980s. It is provided at no cost, is effective against microfilariae (blocking their transmission) and can be administered annually as a single oral dose with ...
Dominique, Richard-Lenoble   +2 more
openaire   +2 more sources

Ivermectin impacts on dung beetle diversity and their ecological functions in two distinct Brazilian ecosystems

Ecological Entomology, 2022
The indiscriminate use of Ivermectin is becoming a frequent scenario in Brazil, one of the largest beef cattle herds in the world, and the second‐highest commercial production, despite this product having harmful effects on non‐target organisms.
C. Correa   +4 more
semanticscholar   +1 more source

Ivermectine

Annales de Dermatologie et de Vénéréologie, 2004
Ivermectin is a semi-synthetic derivative of a macrocyclic lactone. It causes paralysis in many nematodes and arthropodes because of its effect on ion-channels in cell membranes. Ivermectin was first used in veterinary medicine. In man, it was shown to be microfilaricid against Onchocerca volvulus. Most of the adverse reactions following treatment were
openaire   +2 more sources

Ivermectin in scabies

Current Opinion in Infectious Diseases, 2002
The standard treatment for scabies has long been based on topical scabicides. Ivermectin, a broad-spectrum anti-parasitic agent, was first used in veterinary medicine. This drug, active against nematodes and arthropods, is used in humans for the treatment of filariasis.
openaire   +2 more sources

Ivermectin resistance

Parasitology Today, 1993
In this review of ivermectin resistance, Wesley Shoop discusses the definition of resistance, catalogs all known cases of ivermectin resistance, argues that overmectins and milbemycins belong in the same action family, discusses the possibility of resistance in the filariae, and suggests that detection of ivermectin resistance is the area where future ...
openaire   +2 more sources

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