Results 1 to 10 of about 83,877 (250)

Update on Intravenous Immunoglobulin in Neurology: Modulating Neuro-autoimmunity, Evolving Factors on Efficacy and Dosing and Challenges on Stopping Chronic IVIg Therapy

open access: yesNeurotherapeutics, 2021
In the last 25 years, intravenous immunoglobulin (IVIg) has had a major impact in the successful treatment of previously untreatable or poorly controlled autoimmune neurological disorders.
Marinos C Dalakas
exaly   +2 more sources

Efficacy of IVIG (intravenous immunoglobulin) for corona virus disease 2019 (COVID-19): A meta-analysis

open access: yesInternational Immunopharmacology, 2021
Background The benefit of IVIG (Intravenous Immunoglobulin) therapy for COVID-19 remains controversial. We performed a meta-analysis to investigate the efficacy of IVIG treatment in patients with COVID-19. Methods We searched articles from Web of Science,
Yun Li, Wen-xing Peng
exaly   +2 more sources

Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2015
Significance IgG fragment crystallizable domain (Fc) sialylation has emerged as an important but controversial concept for regulating anti-inflammatory activity of antibodies.
Falk Nimmerjahn   +2 more
exaly   +2 more sources

Predictors of Intravenous Immunoglobulin Non‐Responsiveness in Children With Kawasaki Disease [PDF]

open access: yesImmunity, Inflammation and Disease
Background This retrospective study assesses whether the systemic immune‐inflammation index (SII) is a better predictor of intravenous immunoglobulin (IVIG) non‐responsiveness (IVIG‐NR) in children with Kawasaki disease (KD children) than the neutrophil ...
Yun Cheng, Biquan Chen
doaj   +2 more sources

Efficacy of IVIG therapy for patients with sepsis: a systematic review and meta-analysis

open access: yesJournal of Translational Medicine, 2023
Background Sepsis is an overwhelming reaction to infection that comes with high morbidity and mortality. It requires urgent interventions in order to improve outcomes.
Bo Pan   +4 more
semanticscholar   +1 more source

The importance of FcRn in neuro-immunotherapies: From IgG catabolism, FCGRT gene polymorphisms, IVIg dosing and efficiency to specific FcRn inhibitors

open access: yesTherapeutic Advances in Neurological Disorders, 2021
The neonatal Fc receptor (FcRn) binds endogenous IgG and protects it from lysosomal degradation by transporting it back to the cell surface to re-enter the circulation, extending the serum IgG life span.
M. Dalakas, P. Spaeth
semanticscholar   +1 more source

Preliminary study on the effect of IVIG with different Aβ antibody on cognitive function of Alzheimer′s disease model mice

open access: yesZhongguo shuxue zazhi, 2022
Objective To investigate the effect of intravenous immunoglobulin(IVIG) with different Aβ antibody content on the cognitive function of Alzheimer′s disease model mice. Methods IVIG from 8 domestic blood products companies were selected.
Zhangcheng FEI   +7 more
doaj   +1 more source

Perbandingan Terapi Tunggal Kortikosteroid Intravena dengan Kombinasi Imunoglobulin dan Kortikosteroid Intravena pada Pasien Multisystem Inflammatory Syndrome in Children

open access: yesSari Pediatri, 2022
Latar belakang. Tata laksana MIS-C saat ini menggunakan imunoglobulin intravena (IVIG) dan kortikosteroid intravena sebagai dua pilar terapi utama. Mekipun demikian, belum terdapat bukti sahih berupa uji klinis acak terkendali mengenai efektivitas terapi
Yogi Prawira, Nicodemus Suwandy
doaj   +1 more source

ANTI-MOG ASSOCIATED ENCEPHALITIS: WHEN STEROID THERAPY IS NOT ENOUGH [PDF]

open access: yesEuromediterranean Biomedical Journal, 2022
MOG-antibodies are consistently identified in a variety of acquired demyelinating syndromes. In children, the most common presenting phenotype is acute disseminated encephalomyelitis, an immune-mediated disease characterized by demyelination and ...
Piero Pavone
doaj   +1 more source

Intravenous Immunoglobulin (IVIG) Therapy for COVID-19 Omicron (B.1.1.529) Variant with Acute Respiratory Distress Syndrome

open access: yesJournal of Anaesthesia and Pain, 2023
Background: COVID-19 become the pandemic and infect more than million people. The World health organization and other clinical institutions have not yet established a definitive therapy to treat this disease due to a rapid virus mutation and anomaly ...
Dewi Arum Sawitri , Arie Zainul Fatoni
doaj   +1 more source

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