Results 31 to 40 of about 49,735 (302)

Intravenous immunoglobulin in paediatric neurology: safety, adherence to guidelines, and long-term outcome.

, 2016
AIM: Intravenous immunoglobulin (IVIG) is an expensive therapy used in immunodeficiency and autoimmune disorders. Increasing demands and consequent shortages result in a need for usage to conform to guidelines.
Suppiej A, SUPPIEJ, AGNESE, Dale RC, Sartori S, SARTORI, STEFANO, IVIG in Neurology Study Group, Nosadini M, NOSADINI, MARGHERITA, Mohammad SS   +8 more
core   +1 more source

A Comparison Between 1 Day versus 7 Days of Sepsis in Mice with the Experiments on LPS-Activated Macrophages Support the Use of Intravenous Immunoglobulin for Sepsis Attenuation

Journal of Inflammation Research, 2021
Jiradej Makjaroen,1 Arthid Thim-Uam,2 Cong Phi Dang,3 Trairak Pisitkun,1 Poorichaya Somparn,1,4 Asada Leelahavanichkul4– 6 1Center of Excellence in Systems Biology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; 2Division of ...
Makjaroen J, Thim-Uam A, Dang CP, Pisitkun T, Somparn P, Leelahavanichkul A   +5 more
doaj  

Intravenous Immunoglobulin Therapy in COVID-19 Disease

Sakarya Tıp Dergisi, 2021
High dose IVIG has been an appropriate immunomodulatory treatment option for prophylaxis of severe infections in autoimmune and inflammatory diseases [1].
Öner Özdemir, Ayşegül Pala, Elif Şeker   +2 more
doaj   +1 more source

Efficacy and safety of IVIG in CIDP: Combined data of the PRIMA and PATH studies

, 2019
Intravenous immunoglobulin (IVIG) is a potential therapy for chronic inflammatory demyelinating polyneuropathy (CIDP). To investigate the efficacy and safety of the IVIG IgPro10 (Privigen) for treatment of CIDP, results from Privigen Impact on Mobility ...
Cornblath, DR, van Geloven, N, Merkies, ISJ, Lewis, RA, van Schaik, IN, Lawo, JP, Bril, V, Sobue, G, Léger, JM, Sabet, A, Hartung, HP, De Bleecker, JL, Sommer, C, et al., Durn, BL   +14 more
core   +1 more source

Different IVIG glycoforms affect in vitro inhibition of anti-ganglioside antibody-mediated complement deposition [PDF]

, 2014
Intravenous immunoglobulin (IVIG) is the first line treatment for Guillain–Barré syndrome and multifocal motor neuropathy, which are caused by anti-ganglioside antibody-mediated complement-dependent cytotoxicity.
Yamaguchi, Yoshiki, Yuki, Nobuhiro, Peter J Späth, Shahrizaila, Nortina, Nortina Shahrizaila (635406), Makoto Sudo (635402), Peter J. Späth (635403), Benjamin K. Ong (635405), Yoshiki Yamaguchi, Yoshiki Yamaguchi (132437), Kana Matsumoto-Morita (635404), Sudo, Makoto, Benjamin K Ong, Nobuhiro Yuki (60770), Nortina Shahrizaila, Peter J. Späth, Matsumoto-Morita, Kana, Späth, Peter Julius, Makoto Sudo, Ong, Benjamin K., Benjamin K. Ong, Nobuhiro Yuki, Kana Matsumoto-Morita   +22 more
core   +3 more sources

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

Clinical and laboratory parameter analysis in patients with common Variable Immunodeficiency [PDF]

Medicinski Podmladak, 2022
Introduction: Common Variable Immunodeficiency (CVID) is the most prevalent primary immunodeficiency in adult population. The diagnosis is based on low concentration of at least 2 immunoglobulin classes, mostly IgG, with low IgA and/or IgM.
Krtinić Danka, Stojanović Maja
doaj  

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

IVIG Induced Hemolytic Anemia [PDF]

, 2020
Intravenous immunoglobulin (IVIG) is derived from donated plasma used to treat immune deficiency, autoimmune, and inflammatory disorders. Adverse effects occur in 5-15% of patients with hemolytic anemia being a delayed reaction.
Luyeho, Peter, Demertzis, Zachary, Daering, Nicholas J   +2 more
core   +1 more source

The importance of FcRn in neuro-immunotherapies: From IgG catabolism, FCGRT gene polymorphisms, IVIg dosing and efficiency to specific FcRn inhibitors. [PDF]

, 2021
The neonatal Fc receptor (FcRn) binds endogenous IgG and protects it from lysosomal degradation by transporting it back to the cell surface to re-enter the circulation, extending the serum IgG life span.
Dalakas, Marinos C., Späth, Peter J.
core   +2 more sources