Results 51 to 60 of about 49,735 (302)

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

A Randomized Double-Blind Placebo-Control Feasibility Trial of Immunoglobulin Treatment for Prevention of Recurrent Acute Exacerbations of COPD

International Journal of COPD, 2021
Juthaporn Cowan,1,2 Sunita Mulpuru,1,2 Sara J Abdallah,2 Anchal Chopra,3 Andrew Purssell,1 Michaeline McGuinty,1 Gonzalo G Alvarez,1,2 Antonio Giulivi,2,4 Vicente Corrales-Medina,1,2 Derek MacFadden,1,2 Loree Boyle,1 Delvina Hasimja,1 Kednapa Thavorn,2,5,
Cowan J, Mulpuru S, Abdallah SJ, Chopra A, Purssell A, McGuinty M, Alvarez GG, Giulivi A, Corrales-Medina V, MacFadden D, Boyle L, Hasimja D, Thavorn K, Mallick R, Aaron SD, Cameron DW   +15 more
doaj  

Massive immune response against IVIg interferes with response against other antigens in mice: A new mode of action? [PDF]

PLoS ONE, 2017
Administration of high dose intravenous immunoglobulin (IVIg) is widely used in the clinic to treat autoimmune and severe inflammatory diseases. However, its mechanisms of action remain poorly understood.
Laetitia Sordé, Sebastian Spindeldreher, Ed Palmer, Anette Karle   +3 more
doaj   +1 more source

IVIG Treatment Schedule.

, 2013
IVIG Treatment Schedule.
Joris Veltman (431438), Jordan Dimitrakoff (431442), Adam P. Fagin (147181), Theo S. Plantinga (164719), Emeric F. Bojarski (431436), Mihai G. Netea (105648), Alexander Hoischen (195016), Adam C. Strauss (431437), Victor J. Anciano Granadillo (431440), Stephen A. Allsop (431439), Arsani William (431441)   +10 more
core   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Adjunct Topical Human Immunoglobulin IgG Therapy in Dry Eye Disease

Indian Journal of Ophthalmology
Purpose: The aim of this study was to evaluate the role of topical human IgG eye drops (4 mg/mL) as adjunct therapy in eyes with moderate to severe refractory dry eye disease (DED).
Murugesan Vanathi, Livia Khan, Thirumurthy Velpandian, Ashish Dubey, Noopur Gupta, Tulika Seth, Manoranjan Mahapatra, Maroof Ahmed Khan, Sandeep Jain, Radhika Tandon   +9 more
doaj   +1 more source

Liver Failure and Conjugated Hyperbilirubinemia in a Preterm Neonate: Role of Early IVIG and Exchange Transfusion

American Journal of Perinatology Reports, 2018
Neonatal liver failure (NLF) is a rare diagnosis but carries with it significant risks of mortality and morbidity. Common etiologies for NLF include metabolic causes, gestational alloimmune liver disease (GALD or neonatal hemochromatosis), and viral ...
Jayasree Nair, Vasantha H.S. Kumar
doaj   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera, Agnese Tamanti, Silvia Messina, Nicola Dall'Osto, Teresa Maltempo, Stefano Ziccardi, Matteo Foschi, Maria Grazia Piscaglia, Diana Ferraro, Francesco Crescenzo, Francesca Rossi, Albulena Bajrami, Sabrina Marangoni, Damiano Marastoni, Francesca Benedetta Pizzini, Maria Isabel Leite, Roberta Magliozzi, Patrick Waters, Massimiliano Calabrese, Jacqueline Palace, Ruth Geraldes   +20 more
wiley   +1 more source

Guillain–Barré syndrome with bilateral extensor plantar responses: A rare case report

Journal of Family Medicine and Primary Care
Guillain–Barré syndrome (GBS) is an acute immune-mediated polyradiculoneuropathy, typically presenting with rapidly progressive symmetrical limb weakness and areflexia.
Midhun Mohan, Ramakant Yadav, Ajay Emani Ramamurthy   +2 more
doaj   +1 more source

Immunoglobulin for Treating Bacterial Infections: One More Mechanism of Action

Antibodies, 2019
The mechanisms underlying the effects of immunoglobulins on bacterial infections are thought to involve bacterial cell lysis via complement activation, phagocytosis via bacterial opsonization, toxin neutralization, and antibody-dependent cell-mediated ...
Teiji Sawa, Mao Kinoshita, Keita Inoue, Junya Ohara, Kiyoshi Moriyama   +4 more
doaj   +1 more source