Results 51 to 60 of about 83,877 (250)

Prediction of repeated intravenous immunoglobulin resistance in children with Kawasaki disease

BMC Pediatrics, 2021
Background Repeated intravenous immunoglobulin (IVIG) resistance prediction is one of the pivotal topics in Kawasaki disease (KD). Those non-responders of repeated IVIG treatment might be improved by an early-intensified therapy to reduce coronary artery
Yaheng Lu, Tingting Chen, Yizhou Wen, Feifei Si, Xindan Wu, Yanfeng Yang   +5 more
doaj   +1 more source

Predictive value of albumin for intravenous immunoglobulin resistance in a large cohort of Kawasaki disease patients

Italian Journal of Pediatrics, 2023
Background Intravenous immunoglobulin (IVIG) has been the mainstay of treatment for Kawasaki disease (KD) over the past decades. However, 10–20% of KD patients are resistant to IVIG treatment which puts those patients at high risk of coronary artery ...
Rui Zhang, Shuping Shuai, Hongxi Zhang, Jianghui Cai, Na Cui, Mi Tang, Shasha Xing, Yu Gao, Xia Liu, Xiao Yang   +9 more
doaj   +1 more source

Second IVIg course in Guillain‐Barré syndrome patients with poor prognosis (SID‐GBS trial): Protocol for a double‐blind randomized, placebo‐controlled clinical trial

Journal of the peripheral nervous system, 2018
One course of intravenous immunoglobulins (IVIg) of 2 g/kg is standard treatment in Guillain‐Barré syndrome (GBS) patients unable to walk independently.
C. Walgaard, B. Jacobs, Hester F. Lingsma, E. Steyerberg, D. Cornblath, P. V. van Doorn   +5 more
semanticscholar   +1 more source

Allergen-specific IgG as a mediator of allergy inhibition: Lessons from mother to child

Human Vaccines & Immunotherapeutics, 2017
Allergen-specific IgG produced by immune mothers is associated with less predisposition to allergy development in their children. This finding has been described by several groups over the last few decades, but the mechanisms by which maternal IgG can ...
Jefferson Russo Victor
doaj   +1 more source

Treatment Intensification in Patients With Kawasaki Disease and Coronary Aneurysm at Diagnosis. [PDF]

, 2019
BackgroundCoronary artery aneurysms (CAA) are a serious complication of Kawasaki disease. Treatment with intravenous immunoglobulin (IVIg) within 10 days of fever onset reduces the risk of CAA from 25% to <5%.
Baker, Annette L, Burns, Jane C, Dahdah, Nagib, de Ferranti, Sarah D, Dionne, Audrey, Fournier, Anne, Friedman, Kevin G, Gauvreau, Kimberlee, Gould, Patrick, Newburger, Jane W, Son, Mary Beth, Tremoulet, Adriana H   +11 more
core  

Infliximab Plus Intravenous Immunoglobulin (IVIG) Versus IVIG Alone as Initial Therapy in Children With Kawasaki Disease Presenting With Coronary Artery Lesions: Is Dual Therapy More Effective?

The Pediatric Infectious Disease Journal, 2018
Background: We previously demonstrated that 80% of Kawasaki disease (KD) patients who develop coronary artery lesions (CALs) have them at diagnosis.
P. Jone, Marsha S. Anderson, M. Mulvahill, Heather R. Heizer, M. Glodé, S. Dominguez   +5 more
semanticscholar   +1 more source

A comparison of the predictive validity of the combination of the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio and other risk scoring systems for intravenous immunoglobulin (ivig)-resistance in Kawasaki disease

PLoS ONE, 2017
Background We recently reported that the combination of the neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) is a novel and useful predictor of intravenous immunoglobulin (IVIG)-resistance in Kawasaki disease (KD).
S. Takeshita, Takashi Kanai, Y. Kawamura, Yusuke Yoshida, S. Nonoyama   +4 more
semanticscholar   +1 more source

A Randomized Double-Blind Placebo-Control Feasibility Trial of Immunoglobulin Treatment for Prevention of Recurrent Acute Exacerbations of COPD

International Journal of COPD, 2021
Juthaporn Cowan,1,2 Sunita Mulpuru,1,2 Sara J Abdallah,2 Anchal Chopra,3 Andrew Purssell,1 Michaeline McGuinty,1 Gonzalo G Alvarez,1,2 Antonio Giulivi,2,4 Vicente Corrales-Medina,1,2 Derek MacFadden,1,2 Loree Boyle,1 Delvina Hasimja,1 Kednapa Thavorn,2,5,
Cowan J, Mulpuru S, Abdallah SJ, Chopra A, Purssell A, McGuinty M, Alvarez GG, Giulivi A, Corrales-Medina V, MacFadden D, Boyle L, Hasimja D, Thavorn K, Mallick R, Aaron SD, Cameron DW   +15 more
doaj  

Liver Failure and Conjugated Hyperbilirubinemia in a Preterm Neonate: Role of Early IVIG and Exchange Transfusion

American Journal of Perinatology Reports, 2018
Neonatal liver failure (NLF) is a rare diagnosis but carries with it significant risks of mortality and morbidity. Common etiologies for NLF include metabolic causes, gestational alloimmune liver disease (GALD or neonatal hemochromatosis), and viral ...
Jayasree Nair, Vasantha H.S. Kumar
doaj   +1 more source

Massive immune response against IVIg interferes with response against other antigens in mice: A new mode of action? [PDF]

PLoS ONE, 2017
Administration of high dose intravenous immunoglobulin (IVIg) is widely used in the clinic to treat autoimmune and severe inflammatory diseases. However, its mechanisms of action remain poorly understood.
Laetitia Sordé, Sebastian Spindeldreher, Ed Palmer, Anette Karle   +3 more
doaj   +1 more source