Results 71 to 80 of about 49,735 (302)

Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study

open access: yesArthritis Care &Research, EarlyView.
Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali   +11 more
wiley   +1 more source

Distinctive serum lipidomic profile of IVIG-resistant Kawasaki disease children before and after treatment.

open access: yesPLoS ONE, 2023
Kawasaki Disease (KD) is an acute inflammatory disorder associated with systemic vasculitis. Intravenous immunoglobulin (IVIG) is an effective therapy for KD, yet, about 20% of cases show IVIG resistance with persistent inflammation. The lipid profile in
Zhen Chen   +5 more
doaj   +1 more source

Eczematous reaction to IVIG for the treatment of dermatomyositis

open access: yesInternational Journal of Women's Dermatology, 2018
The use of high-dose intravenous immunoglobulin (IVIG) is an accepted therapy for patients with refractory dermatomyositis. Cases of eczematous reactions to IVIG have been reported in the literature, but to our knowledge, none in patients being treated for dermatomyositis.
J. Berk-Krauss   +3 more
openaire   +3 more sources

A differential concentration-dependent effect of IVIg on neutrophil functions: relevance for anti-microbial and anti-inflammatory mechanisms [PDF]

open access: yes, 2011
Background Polymorphonuclear neutrophils (PMN) play a key role in host defences against invading microorganisms but can also potentiate detrimental inflammatory reactions in case of excessive or misdirected responses. Intravenous immunoglobulins (IVIg)
Bayry, Jagadeesh   +18 more
core   +3 more sources

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi   +10 more
wiley   +1 more source

MULTISISTEMSKI VNETNI SINDROM PRI OTROCIH (MIS-C) PO COVID-19: BLAG POTEK BOLEZNI BREZ PRIZADETOSTI SRČNO-ŽILNEGA SISTEMA

open access: yesSlovenska pediatrija
Multisistemski vnetni sindrom pri otrocih (MIS-C) je redko, vendar resno stanje, povezano s predhodno okužbo z viru-som SARS-CoV-2. Običajno se kaže s sistemskim vnetjem, ki je lahko podobno Kawasakijevi bolezni, in lahko prizadene več organskih sistemov,
Teona Lomidze   +8 more
doaj   +1 more source

Maternal Immune Thrombocytopenic Purpura Leading to Severe Neonatal Autoimmune Thrombocytopenia: Report of Two Cases

open access: yesNational Board of Examinations Journal of Medical Sciences
Introduction: In neonatal intensive care units, neonatal thrombocytopenia is one of the common hematological abnormality seen. Neonatal autoimmune thrombocytopenia should be considered in any neonate who is born to a known case of immune thrombocytopenia
Khushwant Kaur   +2 more
doaj   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Intravenous immunoglobulin treatment for encephalitis in children aged 6 months to 16 years: the IgNiTE RCT

open access: yesEfficacy and Mechanism Evaluation
Background There are data suggesting that intravenous immunoglobulin treatment has some benefit for certain forms of encephalitis but robust evidence from large randomised controlled trials in children with all-cause encephalitis is lacking. Objective To
Mildred A Iro   +18 more
doaj   +1 more source

Role of Pyroptosis in IVIG-Resistant Kawasaki Disease and the Establishment of a New Predictive Model [PDF]

open access: yes
Shiyu Li, Yang Zhou, Yini Wen, Yali Wu, Fan Liu, Yan Ding Department of Pediatric Immunology, Wuhan Children’s Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430016, People’s Republic of ...
Wen Y, Ding Y, Li S, Zhou Y, Wu Y, Liu F
core  

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