Results 81 to 90 of about 49,735 (302)

Targeting B‐Cell‐Activating Factor and Its Receptor in Immune Thrombocytopenia and Warm Autoimmune Hemolytic Anemia

American Journal of Hematology, EarlyView.
ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas, Nichola Cooper, Vickie McDonald, Karina Yazdanbakhsh, Wilma Barcellini   +4 more
wiley   +1 more source

IVIG Resistance in Kawasaki Disease: Clinical and Laboratory Risk Factors and the Potential Role of Administration Timing [PDF]

Yue Peng,1– 3,* Fengchuan Jing,1– 3,* Dong Liu,4 Bin Li,5 Yanxia Xu,6 Zhongyou Tan,7 Ouyang Chen,7 Yanfeng Yang,8 Feifei Si,8 Wenliang Jiang,9 Cong Li,9 Zhenli Cheng,1– 3 Xue Zhou,1– 3 Siqi Feng,1– 3 Ya Su,1– 3 Qijian Yi1– 3 1Department ...
Chen O, Peng Y, Li C, Yi Q, Zhou X, Cheng Z, Yang Y, Tan Z, Jiang W, Li B, Si F, Liu D, Su Y, Feng S, Jing F, Xu Y   +15 more
core  

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

GBS and CIDP Spectrum and IVIg treatment [PDF]

, 2018
The spectrum of GBS, CIDP and its subforms is investigated in this thesis. We identified 32 relapsing GBS patients and compared their clinical characteristics with 476 non-recurrent GBS patients.
Kuitwaard, K. (Krista), Kuitwaard, Krista   +1 more
core   +1 more source

Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia

Platelets, 2017
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder characterized by low platelet counts. First-line treatment includes intravenous immunoglobulin (IVIg), however, its working mechanism remains incompletely understood.
Rick Kapur, Rukhsana Aslam, Michael Kim, Li Guo, Heyu Ni, George B. Segel, John W. Semple   +6 more
doaj   +1 more source

A novel combination approach of human polyclonal IVIG and antibiotics against multidrug-resistant Gram-positive bacteria

, 2016
Mariam Madkour Sallam, Khaled Abou-Aisha, Mohamed El-Azizi Department of Microbiology, Immunology, and Biotechnology, Faculty of Pharmacy and Biotechnology, German University in Cairo, New Cairo City, Cairo, Egypt Background: Gram-positive ...
Sallam MM, El-Azizi M, Abou-Aisha K
core  

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness, Ameya S. Walimbe, Emily R. Strouphauer, Michio Hirano, Alejandro D. Iglesias, Valentina Emmanuele, Caitlin C. Griffin, Sheldon L. Kaplan, William A. Gomes, Karen K. Moeller, Stephen F. Kralik, Fernando Scaglia   +11 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Predictive factors of first dosage intravenous immunoglobulin-related adverse effects in children.

PLoS ONE, 2020
BACKGROUND:Intravenous immunoglobulin (IVIG) therapy is used in the treatment of various diseases, and IVIG-related adverse effects (IVIG-AEs) vary from mild to severe.
Jun Kubota, Shin-Ichiro Hamano, Atsuro Daida, Erika Hiwatari, Satoru Ikemoto, Yuko Hirata, Ryuki Matsuura, Daishi Hirano   +7 more
doaj   +1 more source