Results 1 to 10 of about 16,672 (246)

Optimizing tick artificial membrane feeding for Ixodes scapularis. [PDF]

Sci Rep, 2023
AbstractArtificial membrane feeding (AMF) is a powerful and versatile technique with a wide range of applications in the study of disease vectors species. Since its first description, AMF has been under constant optimization and standardization for different tick species and life stages.
Garcia Guizzo M, Meneses C, Amado Cecilio P, Hessab Alvarenga P, Sonenshine D, Ribeiro JM.   +5 more
europepmc   +4 more sources

Genetic manipulation of an Ixodes scapularis cell line

mBio, 2023
Although genetic manipulation is one of the hallmarks of model organisms, its applicability to non-model species has remained difficult due to our limited understanding of their fundamental biology.
Nisha Singh, Agustin Rolandelli, Anya J. O’Neal, L. Rainer Butler, Sourabh Samaddar, Hanna J. Laukaitis-Yousey, Matthew Butnaru, Stephanie E. Mohr, Norbert Perrimon, Joao H. F. Pedra   +9 more
doaj   +3 more sources

Zoonotic Pathogens in Ixodes scapularis, Michigan

Emerging Infectious Diseases, 2007
To the Editor: Ixodes scapularis, the black-legged tick, is the predominant vector of reportable human vectorborne disease in the United States. It transmits agents that cause Lyme borreliosis, human anaplasmosis, and human babesiosis. I. scapularis–borne disease is becoming more frequent as this tick expands its range from tick-endemic foci in the ...
Sarah A. Hamer, Pamela L. Roy, Graham J. Hickling, Edward D. Walker, Erik S. Foster, Christina C. Barber, Jean I. Tsao   +6 more
doaj   +3 more sources

Bartonella infections are rare in blood-fed Ixodes scapularis and Ixodes pacificus ticks collected from rodents in the United States [PDF]

Parasites & Vectors
Background Ixodes scapularis and Ixodes pacificus are important vectors of multiple pathogens in the United States. However, their role in transmission of Bartonella spp., which are commonly reported in rodents and fleas, has been debated.
Ying Bai, Lynn M. Osikowicz, Jacoby Clark, Erik Foster, Christina Parise, Sarah Maes, Rebecca J. Eisen   +6 more
doaj   +2 more sources

mRNA vaccination of rabbits alters the fecundity, but not the attachment, of adult Ixodes scapularis [PDF]

Scientific Reports
19ISP is a nucleoside-modified mRNA-lipid nanoparticle vaccine that targets 19 Ixodes scapularis proteins. We demonstrate that adult I. scapularis have impaired fecundity when allowed to engorge on 19ISP-immunized rabbits.
Jaqueline Matias, Yingjun Cui, Geoffrey E. Lynn, Kathleen DePonte, Emily Mesquita, Hiromi Muramatsu, Mohamad G. Alameh, Garima Dwivedi, Ying K. Tam, Norbert Pardi, Drew Weissman, Erol Fikrig   +11 more
doaj   +2 more sources

Ixodes dammini: A Junior Synonym for Ixodes scapularis [PDF]

Emerging Infectious Diseases, 1998
Martin Sanders
doaj   +3 more sources

Acquired tick resistance in Peromyscus leucopus alters Ixodes scapularis infection [PDF]

Infection and Immunity
Ticks are obligate hematophagous parasites and pathogen vectors responsible for morbidity and mortality worldwide. Ixodes scapularis is a vector for at least seven pathogens relevant to human and animal health, including the Lyme disease microbe ...
Elis A. Fisk, Cassie J. Leonard, Kristin L. Rosche, Elisabeth Ramirez-Zepp, Jeffrey R. Abbott, Jeb P. Owen, Dana K. Shaw   +6 more
doaj   +2 more sources

Sharing the Ride: Ixodes scapularis Symbionts and Their Interactions [PDF]

Frontiers in Cellular and Infection Microbiology, 2020
The deer tick Ixodes scapularis transmits a variety of disease agents in the United States, spreading the bacteria that causes Lyme borreliosis, the protozoan agent of babesiosis, and viruses such as Powassan.
Philip E. Stewart, Marshall E. Bloom
doaj   +3 more sources

Metabolomic changes associated with acquired resistance to Ixodes scapularis

Ticks and Tick-Borne Diseases, 2023
Guinea pigs repeatedly exposed to Ixodes scapularis develop acquired resistance to the ticks (ATR). The molecular mechanisms of ATR have not been fully elucidated, and partially involves immune responses to proteins in tick saliva.
Yingjun Cui, Jaqueline Matias, Xiaotian Tang, Balasubramanian Cibichakravarthy, Kathleen DePonte, Ming-Jie Wu, Erol Fikrig   +6 more
doaj   +4 more sources

Early embryonic development in the tick Ixodes scapularis suggests syncytial organization and cellularization before blastoderm formation [PDF]

EvoDevo
Ixodes ticks are the most important vectors of arthropod-borne diseases in the United States, Canada, and Europe. Ixodes scapularis is the major vector that transmits the causative agent of Lyme disease in the eastern United States and can transmit up to
Isaac A. Hinne, Hailee R. Ciccotti, Jakub Wudarski, Michael N. Pham, Arvind Sharma, Molly M. McVicar, Benjamin Faustino, Andrew B. Nuss, Prashant P. Sharma, Monika Gulia-Nuss   +9 more
doaj   +2 more sources