The highly improved genome of Ixodes scapularis with X and Y pseudochromosomes [PDF]
Life Science Alliance, 2023 Ixodes scapularis Gulia-Nuss (IscGN) genome assembly and gene set were obtained using DNA from eggs and male and female adult ticks. By combining Hi-C, PacBio HiFi, and Illumina sequencing technologies, we assembled 13 pseudoautosomes and sex chromosomes:
Andrew B Nuss +13 more
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Genetic manipulation of an Ixodes scapularis cell line
mBio, 2023 Although genetic manipulation is one of the hallmarks of model organisms, its applicability to non-model species has remained difficult due to our limited understanding of their fundamental biology.
Nisha Singh +9 more
doaj +3 more sources
Sharing the Ride: Ixodes scapularis Symbionts and Their Interactions [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 The deer tick Ixodes scapularis transmits a variety of disease agents in the United States, spreading the bacteria that causes Lyme borreliosis, the protozoan agent of babesiosis, and viruses such as Powassan.
Philip E. Stewart, Marshall E. Bloom
doaj +3 more sources
Optimizing tick artificial membrane feeding for Ixodes scapularis. [PDF]
Sci Rep, 2023 AbstractArtificial membrane feeding (AMF) is a powerful and versatile technique with a wide range of applications in the study of disease vectors species. Since its first description, AMF has been under constant optimization and standardization for different tick species and life stages.
Garcia Guizzo M +5 more
europepmc +4 more sources
Zoonotic Pathogens in Ixodes scapularis, Michigan
Emerging Infectious Diseases, 2007 To the Editor: Ixodes scapularis, the black-legged tick, is the predominant vector of reportable human vectorborne disease in the United States. It transmits agents that cause Lyme borreliosis, human anaplasmosis, and human babesiosis. I. scapularis–borne disease is becoming more frequent as this tick expands its range from tick-endemic foci in the ...
Sarah A. Hamer +6 more
doaj +3 more sources
Ixodes dammini: A Junior Synonym for Ixodes scapularis [PDF]
Emerging Infectious Diseases, 1998 Martin Sanders
doaj +3 more sources
Acquired tick resistance in Peromyscus leucopus alters Ixodes scapularis infection [PDF]
Infection and ImmunityTicks are obligate hematophagous parasites and pathogen vectors responsible for morbidity and mortality worldwide. Ixodes scapularis is a vector for at least seven pathogens relevant to human and animal health, including the Lyme disease microbe ...
Elis A. Fisk +6 more
doaj +2 more sources
Metabolomic changes associated with acquired resistance to Ixodes scapularis
Ticks and Tick-Borne Diseases, 2023 Guinea pigs repeatedly exposed to Ixodes scapularis develop acquired resistance to the ticks (ATR). The molecular mechanisms of ATR have not been fully elucidated, and partially involves immune responses to proteins in tick saliva.
Yingjun Cui +6 more
doaj +4 more sources
mRNA vaccination of rabbits alters the fecundity, but not the attachment, of adult Ixodes scapularis [PDF]
Scientific Reports19ISP is a nucleoside-modified mRNA-lipid nanoparticle vaccine that targets 19 Ixodes scapularis proteins. We demonstrate that adult I. scapularis have impaired fecundity when allowed to engorge on 19ISP-immunized rabbits.
Jaqueline Matias +11 more
doaj +2 more sources
Bartonella infections are rare in blood-fed Ixodes scapularis and Ixodes pacificus ticks collected from rodents in the United States [PDF]
Parasites & VectorsBackground Ixodes scapularis and Ixodes pacificus are important vectors of multiple pathogens in the United States. However, their role in transmission of Bartonella spp., which are commonly reported in rodents and fleas, has been debated.
Ying Bai +6 more
doaj +2 more sources