Results 11 to 20 of about 7,279 (169)

Genetic manipulation of an Ixodes scapularis cell line

open access: yesmBio, 2023
Although genetic manipulation is one of the hallmarks of model organisms, its applicability to non-model species has remained difficult due to our limited understanding of their fundamental biology.
Nisha Singh   +9 more
doaj   +3 more sources

Copy Number Variation-Based Molecular Sexing of <i>Ixodes scapularis</i> and <i>Rhipicephalus microplus</i> Immature Stages Using qPCR and ddPCR Approaches. [PDF]

open access: yesEcol Evol
We developed and validated a copy number variation (CNV)‐based molecular method to accurately determine the sex of immature ticks, Ixodes scapularis and Rhipicephalus microplus, which lack morphological sexual dimorphism. Using qPCR and ddPCR assays targeting female‐enriched genes, sex was reliably identified from DNA extracted non‐destructively from a
Sharma A   +11 more
europepmc   +2 more sources

When Clades Collide: Genomic Admixture in Blacklegged Ticks (Ixodes scapularis) From the Great Plains. [PDF]

open access: yesMol Ecol
ABSTRACTIxodes scapularis ticks transmit a number of pathogens important to human health, including Borrelia burgdorferi sensu stricto, the causative agent of Lyme disease. While I. scapularis is found across the Eastern United States, Lyme disease transmission is largely limited to the Northeast and Upper Midwest and is nearly absent in the South ...
Herzog KS   +15 more
europepmc   +2 more sources

Characterization of a Monanema nematode in Ixodes scapularis [PDF]

open access: yesParasites & Vectors, 2020
Abstract Background Metagenomic studies have revealed the presence of a filarial nematode in Ixodes scapularis . The phylogeny of this agent, and its potential for human infection, are unknown.
Rafal Tokarz   +3 more
openaire   +5 more sources

Zoonotic Pathogens in Ixodes scapularis, Michigan

open access: yesEmerging Infectious Diseases, 2007
To the Editor: Ixodes scapularis, the black-legged tick, is the predominant vector of reportable human vectorborne disease in the United States. It transmits agents that cause Lyme borreliosis, human anaplasmosis, and human babesiosis. I. scapularis–borne disease is becoming more frequent as this tick expands its range from tick-endemic foci in the ...
Sarah A. Hamer   +6 more
doaj   +3 more sources

Metabolomic changes associated with acquired resistance to Ixodes scapularis

open access: yesTicks and Tick-Borne Diseases, 2023
Guinea pigs repeatedly exposed to Ixodes scapularis develop acquired resistance to the ticks (ATR). The molecular mechanisms of ATR have not been fully elucidated, and partially involves immune responses to proteins in tick saliva.
Yingjun Cui   +6 more
doaj   +4 more sources

A snapshot of the Ixodes scapularis degradome [PDF]

open access: yesGene, 2011
Parasitic encoded proteases are essential to regulating interactions between parasites and their hosts and thus they represent attractive anti-parasitic druggable and/or vaccine target. We have utilized annotations of Ixodes scapularis proteases in gene bank and version 9.3 MEROPS database to compile an index of at least 233 putatively active and 150 ...
Albert, Mulenga, Kelly, Erikson
openaire   +2 more sources

Sharing the Ride: Ixodes scapularis Symbionts and Their Interactions [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
The deer tick Ixodes scapularis transmits a variety of disease agents in the United States, spreading the bacteria that causes Lyme borreliosis, the protozoan agent of babesiosis, and viruses such as Powassan. However, a variety of other organisms have also evolved symbiotic relationships with this tick species, and it seems likely that some of these ...
Philip E. Stewart, Marshall E. Bloom
openaire   +3 more sources

Tick Cell Culture Analysis of Growth Dynamics and Cellular Tropism of Rickettsia buchneri, an Endosymbiont of the Blacklegged Tick, Ixodes scapularis

open access: yesInsects, 2021
The blacklegged tick, Ixodes scapularis, a species of significant importance to human and animal health, harbors an endosymbiont Rickettsia buchneri sensu stricto.
Cody J. Thorpe   +3 more
doaj   +1 more source

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