Genetic manipulation of an Ixodes scapularis cell line [PDF]
Although genetic manipulation is one of the hallmarks of model organisms, its applicability to non-model species has remained difficult due to our limited understanding of their fundamental biology.
Nisha Singh +9 more
doaj +4 more sources
Characterization of a Monanema nematode in Ixodes scapularis [PDF]
Abstract Background Metagenomic studies have revealed the presence of a filarial nematode in Ixodes scapularis . The phylogeny of this agent, and its potential for human infection, are unknown.
Rafal Tokarz +3 more
core +8 more sources
Two Anaplasma phagocytophilum Strains in Ixodes scapularis Ticks, Canada [PDF]
We developed PCR-based assays to distinguish a human pathogenic strain of Anaplasma phagocytophilum, Ap-ha, from Ap-variant 1, a strain not associated with human infection. The assays were validated on A.
Chantel N. Krakowetz +3 more
doaj +2 more sources
Filarial Nematode Infection in Ixodes scapularis Ticks Collected from Southern Connecticut [PDF]
It was recently demonstrated that the lone star tick Amblyomma americanum could harbor filarial nematodes within the genus Acanthocheilonema. In this study, Ixodes scapularis (deer) ticks collected from Southern Connecticut were evaluated for their ...
Pabbati Namrata +6 more
doaj +3 more sources
TROSPA, an Ixodes scapularis Receptor for Borrelia burgdorferi [PDF]
The Lyme disease agent Borrelia burgdorferi naturally persists in a cycle that primarily involves ticks and mammals. We have now identified a tick receptor (TROSPA) that is required for spirochetal colonization of Ixodes scapularis. B. burgdorferi outer surface protein A, which is abundantly expressed on spirochetes within the arthropod and essential ...
Pal, Utpal +13 more
openaire +4 more sources
The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease [PDF]
A novel L-glutamate-gated anion channel (IscaGluCl1) has been cloned from the black-legged tick, Ixodes scapularis, which transmits multiple pathogens including the agents of Lyme disease and human granulocytic anaplasmosis. When mRNA encoding IscaGluCl1
Shogo Furutani +10 more
doaj +3 more sources
Efficacy of afoxolaner against Ixodes scapularis ticks in dogs [PDF]
Efficacy of afoxolaner, a novel isoxazoline insecticide/acaricide, against Ixodes scapularis was evaluated in a laboratory study. One day prior to treatment, beagle dogs (n=16) were infested with 50 unfed wild adult ticks. Repeat infestations were performed weekly for four additional weeks.
Mitchell, Elizabeth B. +3 more
openaire +3 more sources
Ixodes dammini: A Junior Synonym for Ixodes scapularis [PDF]
Martin Sanders
doaj +3 more sources
Contrasting epigenetics of Ixodes scapularis populations
Hard ticks are a source of public health concern, in part due to their ability to inhabit different environments. In the United States (US), blacklegged ticks (Ixodes scapularis Say), the primary vector of Lyme disease, exhibit various phenotypes ...
Stephanie Guzman-Valencia +18 more
doaj +2 more sources
Zoonotic Pathogens in Ixodes scapularis, Michigan
To the Editor: Ixodes scapularis, the black-legged tick, is the predominant vector of reportable human vectorborne disease in the United States. It transmits agents that cause Lyme borreliosis, human anaplasmosis, and human babesiosis. I. scapularis–borne disease is becoming more frequent as this tick expands its range from tick-endemic foci in the ...
Sarah A. Hamer +6 more
doaj +3 more sources

