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Ahmed OA, Ghanem AS, Móré M, Nagy AC.
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Small retro-inverso peptides recognize mhc class ii ula dr(a, j31*0401)
Protein & Peptide Letters, 1997Abstract: We have synthesized a series of retro-inverso D-peptide analogues and a peptoid analog that mimic potent seven residue L-peptide ligands for DR(a. Pl*0401). The L-peptide ligands compete against binding of a 13 residue biotinylated ligand, HA307-319 (ICso 60nM), with competing peptide ICsos ranging from 30-200nM.The highest affinity heptamer
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Background The effect of CAG repeats on brain function below disease threshold has not been studied thoroughly. We sought to evaluate the possibility of assortative mating in a group of subjects recruited from the community and with no family history of Huntington’s.
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