Results 1 to 10 of about 1,532 (182)

ADS-J21 is a novel HIV-1 entry inhibitor targeting gp41 [PDF]

Current Research in Microbial Sciences
HIV-1 envelope glycoprotein gp41 mediates fusion between HIV-1 and host cell membranes, making inhibitors of gp41 attractive anti-HIV drugs. We previously reported an efficient HIV-1 fusion inhibitor, ADS-J1, with a Y-shaped structure.
Ruiying Liang, Dou Dou, Chunying Wang, Shanshan Huo, Yang Wu, Juan Wang, Zhengsen Yu, Shuomin Zhang, Jingjing Xu, Yue Liu, Peng Liu, Shibo Jiang, Fei Yu   +12 more
doaj   +4 more sources

Dispersive Full-Channel Jones Matrix Modulation in Elliptical Polarization Bases via a Single-Layered Metasurface. [PDF]

Adv Sci (Weinh)
This work presents a dispersive full‐channel Jones matrix modulation strategy using single‐layer metasurface. By synergizing wavelength dispersion engineering with elliptical polarization bases, independent control of four Jones matrix channels is achieved across multiple wavelengths.
He H, Cao G, Zhang S, Xu H, Chen Z, Peng M, Jiang Y, Hu Y, Jing H, Duan H, Yang H.   +10 more
europepmc   +2 more sources

Impact of Wildfire Smoke on Respiratory Disease Associated Healthcare Utilization in Gang-Won Province, South Korea, in 2017. [PDF]

Geohealth
Abstract This study aimed to elucidate the association between wildfire smoke exposure and healthcare utilization for respiratory diseases in Samcheok (City), Gangwon Province, South Korea, focusing on a major wildfire that occurred on 6–9 May 2017. The relative risks (RRs) of healthcare utilization for respiratory diseases in a direct‐exposure area ...
Lee MT, Cha H, Lee JW, Baik J, Jung HI, Moon KM, Jun C, Jung SY, Gu KM.   +8 more
europepmc   +2 more sources

Covalent drug rescue of multiple p53 mutants by stabilizing vinyl sulfone fragments hints to a specific refolding mechanism for R282W. [PDF]

Protein Sci
Abstract The tumor suppressor protein p53 plays a crucial role in cell cycle regulation. In approximately 50% of all tumors, mutations in p53 are observed. Although the top hot spot mutations impair DNA binding, other mutations affect the thermal stability of the protein, leading to its rapid denaturation in physiological conditions.
Stahlecker J, Klett T, Spiegel R, Schwer M, Mier F, Aldea S, Masberg B, Lämmerhofer M, Stehle T, Böckler FM.   +9 more
europepmc   +2 more sources

Antenatal Corticosteroid Administration and Childhood Respiratory Morbidity: A Regression Discontinuity Study. [PDF]

BJOG
ABSTRACT Objective To determine if routine administration of antenatal corticosteroids affects the risk of infant lower respiratory tract infection and/or childhood asthma. Design Linked population‐based cohort analysed using a regression discontinuity design, which better controls for confounding than standard observational studies.
Hutcheon JA, Hutcheon JA, Harper S, Cordingley MC, Liauw J, Skoll MA, Socha PM, Srour M, Ting JY, Strumpf EC.   +9 more
europepmc   +2 more sources

Repeated weighting in mixed-mode censuses

Economics and Business Review, 2021
The main aim of the paper is to use the repeated weighting (RW) method on data from the National Census of Population and Housing 2011 (NCPH) and Labour Force Survey (LFS) to ensure consistency between margins of final tables derived from different ...
Szymkowiak Marcin, Wilak Kamil
doaj   +1 more source

Influence of the COVID-19 pandemic on the transition of people on the Polish labor market – hidden threats

International Journal of Management and Economics, 2023
The article analyzes changes on the Polish labor market after the outbreak of the COVID-19 pandemic. It aims to assess the effect of the SARS-CoV-2 pandemic on the transition of people on the labor market in Poland.
Węgrzyn Grażyna
doaj   +1 more source

Sectoral changes of employment in Poland during the COVID-19 pandemic: Are reallocation shock effects applicable?

Economics and Business Review, 2022
The aim of this study is to analyse changes in employment and their determinants in twenty sectors of economic activity in Poland during the COVID-19 pandemic. The study focuses on the direct short-run employment effects. The changes in employment in the
Kwiatkowski Eugeniusz, Szymańska Agata
doaj   +1 more source

An Analysis of Important Sectors in Economic Growth. Case Study for Kosova

SEEU Review, 2023
Education, innovation, the labour force, and new businesses are considered the key important sectors (factors) for developed and emerging economies. The paper analyses are performed by using the Cobb Douglas production function for analysing the impact ...
Zogjani Jeton, Kovaci-Uruci Fife, Zogjani Agon   +2 more
doaj   +1 more source

Allocating fiscal stimulus during COVID-19 crisis based on sectoral linkages in Egypt for increasing growth and reducing unemployment [PDF]

Journal of Humanities and Applied Social Sciences, 2021
Purpose – This paper aims to study the inter-sectoral linkages in the Egyptian economy, to increase the efficiency of allocating L.E 100bn fiscal stimulus package (FSP) to tackle the economic fallout from COVID-19 based on the strength of the backward ...
Mai Mohsen Ibrahim, Ola Elkhawaga, Adla Ragab   +2 more
doaj   +1 more source