Results 21 to 30 of about 919,385 (310)
Gut Microbes, 2023 The Salmonella biofilm-associated amyloid protein, curli, is a dominant instigator of systemic inflammation and autoimmune responses following Salmonella infection.
Shingo Bessho +8 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Equivalence between various Shape Preserving Approximations of periodic functions
Researches in MathematicsWe show that the validity of Jackson-type estimates in comonotone and coconvex approximations of continuous $2\pi$-periodic functions by trigonometric polynomials is equivalent to the validity of the corresponding estimates of approximation by continuous
D. Leviatan, O.V. Motorna, I.O. Shevchuk
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Эпилепсия и пароксизмальные состояния, 2021 The report shows that V.A. Karlov proved at the current level of knowledge the correctness of the ideas of the great English neurologist John Hughlings Jackson, author of works on localization of the projection motor centers of the cerebral cortex, on ...
K. Yu. Mukhin
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Jackson County comprehensive plan [PDF]
, 2004 516 pp. First comprehensive plan adopted June 22, 1972. Current plan first adopted 1983. Most recent update March 12, 2004. Referenced Comprehensive Plan Map not included.
Jackson County (Or.)
core
Comparação da composição corporal utilizando dobras cutâneas e bioimpedância em adultos jovens
Revista Brasileira de Nutrição Esportiva, 2021 A avaliação da composição corporal é de grande importância para que profissionais da área da saúde possam obter informações individuais de qualidade, e assim propor as melhores estratégias para a obtenção dos objetivos.
Jean Carlos Pancine de Oliveira +2 more
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source