Results 181 to 190 of about 577,308 (213)

JAK2 V617F mutation is uncommon in patients with the 3q21q26 syndrome

Human Pathology, 2010
The 3q21q26 syndrome is recognized as a distinct clinicopathologic entity. Patients have a myeloid neoplasm associated with 3q21q26 cytogenetic abnormalities and present with anemia, leukopenia, and either thrombocytosis or a normal platelet count associated with dysplasia.
Pei, Lin, Rajyalakshmi, Luthra, Roberto H, Nussenzveig, L Jeffrey, Medeiros   +3 more
openaire   +2 more sources

Absence of FLT3 and JAK2 (V617F) Mutations in Langerhans Cell Histiocytosis

Blood, 2008
Abstract Langerhans cell histocytosis (LCH) is a neoplasm of histiocytic cells believed to be derived from cells of the dendritic system, but the disease pathogenesis is unknown. FMS-like tyrosine kinase 3 (FLT3) is a type III receptor tyrosine kinase that is expressed on the surface of hematopoietic stem cells and plays an important ...
Malak, Abedalthagafi, Huimin, Guo, Dan-Paul, Hartmann, Metin, Ozdemirli   +3 more
openaire   +2 more sources

V617F mutation in JAK2 is associated with poorer survival in idiopathic myelofibrosis

Blood, 2006
Most patients with polycythemia vera and half with idiopathic myelofibrosis and essential thrombocythemia have an acquired V617F mutation in JAK2. Using sensitive polymerase chain reaction (PCR)-based methods, we genotyped 152 patients with idiopathic myelofibrosis to establish whether there were differences in presentation and outcome between those ...
Campbell, Peter J, Griesshammer, Martin, Döhner, Konstanze, Döhner, Hartmut, Kusec, Rajko, Hasselbalch, Hans C, Larsen, Thomas Stauffer, Pallisgaard, Niels, Giraudier, Stéphane, Le Bousse-Kerdilès, Marie-Caroline, Desterke, Christophe, Guerton, Bernadette, Dupriez, Brigitte, Bordessoule, Dominique, Fenaux, Pierre, Kiladjian, Jean-Jacques, Viallard, Jean-François, Brière, Jean, Harrison, Claire N, Green, Anthony R, Reilly, John T   +20 more
openaire   +3 more sources

JAK2 (V617F) Mutation and Cerebral Venous Thrombosis,

Blood, 2011
Abstract Abstract 3339 Background. Whether or not cerebral venous thrombosis, such as splanchnic venous thrombosis, can be the first manifestation of an underlying myeloproliferative neoplasm is currently unclear. Methods.
Ida Martinelli, Serena Maria Passamonti, Eugenia Biguzzi, Franca Franchi, Francesca Gianniello, Paolo Bucciarelli, Daniela Pietra, Pier Mannuccio Mannucci, Mario Cazzola   +8 more
openaire   +1 more source

JAK2 V617F mutation positives in the general population.

Journal of Clinical Oncology, 2010
6599 Background: The JAK2 V617F mutation is a somatic mutation in the JAK2 gene resulting in cell autonomuos overproduction of myeloid cells.
S. E. Bojesen, C. Nielsen, H. Birgens, B. G. Nordestgaard, L. Kjaer, H. Hasselbalch   +5 more
openaire   +1 more source

Myeloid Blasts in Transformed JAK2-V617F Positive Myeloproliferative Disorders Are Frequently Negative for the JAK2-V617F Mutation.

Blood, 2006
Abstract Acute myeloid leukemia (AML) is a common complication of myeloproliferative disorders (MPDs). The role of the JAK2-V617F mutation in this process is unknown. We performed a retrospective analysis of DNA samples from MPD patients with secondary AML.
Theocharides, Alexandre, Boissinot, Marjorie, Garand, Richard, Girodon, François, Teo, Soon-Siong, Lippert, Eric, Tichelli, Andre, Hermouet, Sylvie, Skoda, Radek C.   +8 more
openaire   +2 more sources

V617F mutation in JAK2 is associated idiopathic myelofibrosis

Blood, 2006
Most patients with polycythemia vera and half with idiopathic myelofibrosis and essential thrombocythemia have an acquired V617F mutation in JAK2. Using sensitive PCR-based methods, we genotyped 152 patients with idiopathic myelofibrosis in order to establish whether there were differences in presentation and outcome between those with and those ...
Campbell, Peter, Griesshammer, Martin, Dohner, Konstanze, Dohner, Hartmut, Kušec, Rajko, Hasselbalch, Hans, Larsen, Thomas, Pallisgaard, Niels, Giraudier, Stephane, Le Bousse-Kerdiles, Marie Caroline, Desterke, Christophe, Guerton, Bernadette, Dupriez, Brigitte, Bordessoule, Dominique, Fenaux, Pierre, Kiladjian, Viallard Jean-Jacques F., Briere, Jean, Harrison, Claire N., Green, Anthony A., Reilly, John T.   +19 more
openaire   +2 more sources

JAK2 V617F mutation is not involved in thromboembolism in IBD

Inflammatory Bowel Diseases, 2008
Karimi, O., Crusius, J.B.A., Coucoutsi, C., Heijmans, R, Sambuelli, A.M., Pena, A.S., Koutroubakis, I.E.   +6 more
openaire   +3 more sources

The JAK2 V617F mutational status and allele burden

Thrombosis Research, 2015
Shanshan, Liang, Yanhong, Zhou
openaire   +2 more sources

CRISPR/Cas12a-Based Ultrasensitive and Rapid Detection of JAK2 V617F Somatic Mutation in Myeloproliferative Neoplasms

Biosensors, 2021
Zhuo Li, Chunhua Zhang, Zhiqing Hu
exaly