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Familial essential thrombocythemia
The American Journal of Medicine, 1986Primary or essential thrombocythemia is rarely observed in childhood, and familial occurrence has been reported only once. In this study, essential thrombocythemia is documented in five members of both sexes from two to 62 years of age in three successive generations.
M E, Eyster +6 more
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Essential Thrombocythemia in Children
Journal of Pediatric Hematology/Oncology, 1999The objective of this study was to evaluate the clinical course, laboratory findings, and outcomes of children with essential thrombocythemia (ET).The authors analyzed 36 children, ages 6 weeks to 18 years, by combining descriptions of 2 patients observed at their institution with 34 patients reported in the English medical literature.Fifteen patients (
Y, Dror, A, Zipursky, V S, Blanchette
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Management of Essential Thrombocythemia
Hematology, 2011Abstract Essential thrombocythemia (ET) is a Philadelphia chromosome (Ph)–negative myeloproliferative neoplasm (MPN) characterized by thrombocytosis and megakaryocytic hyperplasia of the bone marrow, with presence of the JAK2 V617F mutation in 50%-60% of patients. ET evolves to myelofibrosis in a minority of cases, whereas transformation
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Pipobroman therapy of essential thrombocythemia
European Journal of Haematology, 1986We report our results with pipobroman (PB) therapy in patients with essential thrombocythemia (ET). 21 consecutive untreated patients were treated with PB from 1975 to 1984. PB was given at a dose of 1 mg/kg/d until platelet count dropped below 600 × 109/l. In 18 patients (86%) a hematological remission was obtained.
MAZZUCCONI, Maria Gabriella +6 more
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The pathogenesis of essential thrombocythemia
Current Opinion in Hematology, 2011The identification of new mutations continues to further our understanding of the molecular pathogenesis of essential thrombocythemia and related disorders, and offers opportunities for improvements in diagnosis, risk stratification and disease classification.Molecular lesions in essential thrombocythemia affect two distinct pathways: cytokine ...
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Current management strategies for polycythemia vera and essential thrombocythemia
Blood Reviews, 2020Paola Guglielmelli +1 more
exaly
The Journal for Nurse Practitioners, 2023
Ruth Madden Foreman, Richard Brzustowicz
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Ruth Madden Foreman, Richard Brzustowicz
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