Results 11 to 20 of about 15,163 (213)

Essential thrombocythemia [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2007
Essential thrombocythemia (ET) is an acquired myeloproliferative disorder (MPD) characterized by a sustained elevation of platelet number with a tendency for thrombosis and hemorrhage. The prevalence in the general population is approximately 30/100,000.
Brière Jean B
doaj   +6 more sources

Essential thrombocythemia: a rare disease in childhood

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2013
Essential thrombocythemia is an acquired myeloproliferative disorder characterized by the proliferation of megakaryocytes in bone marrow, leading to a persistent increase in the number of circulating platelets and thus increasing the risk for thrombotic ...
Julia Maimone Beatrice   +1 more
doaj   +2 more sources

Analysis of phenotype and outcome in essential thrombocythemia with CALR or JAK2 mutations [PDF]

open access: yesHaematologica, 2015
The JAK2 V617F mutation, the thrombopoietin receptor MPL W515K/L mutation and calreticulin (CALR) mutations are mutually exclusive in essential thrombocythemia and support a novel molecular categorization of essential thrombocythemia.
Carla Al Assaf   +12 more
doaj   +2 more sources

Emerging treatments for essential thrombocythemia

open access: yesJournal of Blood Medicine, 2011
Steven Okoli, Claire HarrisonDepartment of Haematology, Guy's and St Thomas' NHS Foundation Trust, Great Maze Pond, London, UKAbstract: In 1934, Epstein and Goedel used the term hemorrhagic thrombocythemia to describe a disorder ...
Okoli S, Harrison C
doaj   +2 more sources

Essential Thrombocythemia

open access: yesSiriraj Medical Journal, 2002
This is a review of twelve cases of Essential Thrombocythemia at Suratthani Hospital, aged between 48 to 87 years old, 6 male and 6 female. The initial clinical presentations were as follows: 2 asymptomatic cases (incidentally found on routine CBC check ...
Kanchanee Janwanitsthaporn
doaj   +1 more source

Essential thrombocythemia, hemolytic anemia and hepatic cirrhosis: Could there be an association?

open access: yesHematology Reports, 2018
Vascular events are the most common clinical complication of essential thrombocythemia, leading to sign and symptoms of this disease. There are various sign and symptoms of essential thrombocythemia, such as thrombosis in artery or vein, and enlarged ...
Nata Pratama Hardjo Lugito   +4 more
doaj   +3 more sources

Acute megakaryoblastic transformation from essential thrombocythemia

open access: yesHuman Pathology: Case Reports, 2017
Essential thrombocythemia (ET) is a Philadelphia chromosome-negative myeloproliferative neoplasm characterized by sustained thrombocytosis. Its transformation into acute leukemia is a rare event (5% at 20 years).
Tariq M. Roshan   +3 more
doaj   +2 more sources

Distinguishing essential thrombocythemia JAK2V617F from polycythemia vera: limitations of erythrocyte values

open access: yesHaematologica, 2019
Distinguishing essential thrombocythemia JAK2V617F from polycythemia vera is difficult because of shared mutation and phenotypic characteristics. The World Health Organization suggested hemoglobin and hematocrit values to diagnose polycythemia vera (PV),
Richard T. Silver, Spencer Krichevsky
doaj   +3 more sources

The role of oxidative stress in essential thrombocythemia [PDF]

open access: yesArchives of the Balkan Medical Union, 2018
In patients with myeloproliferative neoplasms (MPNs), including essential thrombocythemia, current studies have demonstrated a JAK2V617F-dependent reactive oxygen species (ROS) elevation partially mediated by a decrease in catalase expression associated ...
Cornel Moisă   +6 more
doaj   +1 more source

Essential thrombocythemia presenting as digital ischemia

open access: yesBangabandhu Sheikh Mujib Medical University Journal, 2017
Essential thrombocythemia is a myeloproliferative disease and is characterized by increased production of platelet and increased megakaryocytes in the bone marrow.
Md. Nazmul Hasan   +5 more
doaj   +3 more sources

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