Results 21 to 30 of about 15,163 (213)

Diagnosis and Management of Essential Thrombocythemia: A Comprehensive Review [PDF]

Documenta Haematologica
Myeloproliferative neoplasms, including essential thrombocythemia, are characterized by clonal proliferations of hematopoietic stem cells, leading to an increase in mature myeloid lineage cells.
Sandra LAZAR, Despina Calamar POPOVICI, Oana SARAU, Hortensia IONITA, Claudiu Octavian IONITA, Dacian Nicolae OROS, Ioana IONITA   +6 more
doaj   +2 more sources

Familial Essential Thrombocythemia Associated with MPL W515L Mutation in Father and JAK2 V617F Mutation in Daughter [PDF]

Case Reports in Hematology, 2014
Familial essential thrombocythemia features the acquisition of somatic mutations and an evolution similar to the sporadic form of the disease. Here we report two patients—father and daughter—with essential thrombocythemia who displayed a heterogeneous ...
Adrian P. Trifa, Andrei Cucuianu, Radu A. Popp   +2 more
doaj   +2 more sources

Pseudotumor Cerebri Syndrome and Essential Thrombocythemia: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Pseudotumor cerebri syndrome (PTCS) is characterized by elevated intracranial pressure in the absence of intracranial mass lesions, structural abnormalities, or infectious conditions. Although the exact pathogenesis of PTCS remains largely elusive, it is increasingly recognized as a multifactorial condition.
Chang FT, Chen YY, Lin FY.
europepmc   +2 more sources

Essential Thrombocythemia [PDF]

New England Journal of Medicine, 2020
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Elisa, Rumi, Mario, Cazzola
openaire   +5 more sources

Essential Thrombocythemia among Patients with Myeloproliferative Neoplasms in Haematology Unit of a Tertiary Care Centre: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association, 2022
Introduction: Essential thrombocythemia, a myeloproliferative condition with an increased number of circulating platelets, is a rare hematological malignancy. The aim of the study is to find out the prevalence of essential thrombocythemia among patients
Sanjit Kumar Sah, Sangam Shah, Sansar Babu Tiwari, Basanta Sharma Poudel, Biranmol Singh, Prakash Sharma, Sunil Sharma Acharya, Hritik Murarka, Sabin Thapaliya, Anjan Shrestha   +9 more
doaj   +1 more source

Thrombospondin in essential thrombocythemia [PDF]

Blood, 1986
Abstract Essential thrombocythemia is a myeloproliferative disorder characterized by frequent bleeding and thrombotic complications. On a molecular level, two abnormalities of platelet thrombospondin have been identified: abnormal glycosylation of the intact 185,000-dalton chain has been detected and a shortened form of the ...
J, Lawler, A M, Cohen, F C, Chao, D J, Moriarty   +3 more
openaire   +3 more sources

Retinal neovascularization in the setting of -mutation positive essential thrombocythemia

SAGE Open Medical Case Reports, 2023
Patients with Calreticulin ( CALR ) mutation positive essential thrombocythemia are often thought of as having a “low-risk” of thrombotic complications.
Stanton P Heydinger, Marwan R Abdulaal, Angeline L Wang   +2 more
doaj   +1 more source

Essential thrombocythemia (ET) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
The disease is a chronic myeloproliferative disorder originating from a mutated pluripotent stem cell capable of producing red blood cells, granulocytes and megakaryocytes. In some cases, B-lymphocyte involvement by the clonal proliferation was documented.
CUNEO, Antonio, CAVAZZINI, Francesco
openaire   +2 more sources

Dynamics of mutations in patients with essential thrombocythemia treated with imetelstat. [PDF]

, 2020
In a phase-2 study, the telomerase inhibitor imetelstat induced rapid hematologic responses in all patients with essential thrombocythemia who were refractory or intolerant to prior therapies.
Snyder, David S., Olatoyosi Odenike, Gabriela M. Baerlocher, Gary Spitzer, David S. Snyder, Oliver G. Ottmann, McDevitt, Michael A, Michael A. McDevitt, Röth, Alexander, Alexander Röth, Ottmann, Oliver G., Spitzer, Gary, Monika Haubitz, Bart Burington, Oppliger Leibundgut, Elisabeth, Odenike, Olatoyosi, Ottmann, Oliver G, Baerlocher, Gabriela M., Haubitz, Monika, Snyder, David S, Burington, Bart, Elisabeth Oppliger Leibundgut, McDevitt, Michael A.   +22 more
core   +1 more source

Frequent reduction or absence of detection of the JAK2-mutated clone in JAK2V617F-positive patients within the first years of hydroxyurea therapy

Haematologica, 2008
We analyzed the effect of hydroxyurea on the JAK2V617F allelic ratio (%JAK2V617F), measured in purified blood granulocytes, of patients with polycythemia vera and essential thrombocythemia.
François Girodon, Céline Schaeffer, Cédric Cleyrat, Morgane Mounier, Ingrid Lafont, Frédéric Dos Santos, Aurélie Vidal, Marc Maynadié, Sylvie Hermouet   +8 more
doaj   +1 more source