Results 101 to 110 of about 114,094,772 (295)
Buletin Ilmiah Nagari Membangun, 2019 Nagari Koto Tinggi which located in Gunuang Omeh Subdistrict in Regency 50 Kota is one of the biggest producers natural products of orange in West Sumatra. Jeruk Siam Gunuang Omeh (JESIGO), has good quality, but post-harvest processing is still lacking.
Weriantoni Weriantoni, Nadailla Mahsyuri
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
JAM-C is constitutively trafficked from endothelial cell junctions.
, 2019 (A) Schematic of the endocytosis of endogenous JAM-C from the endothelial cell surface showing the extracellular immunoglobulin domains (blue) and the intracellular PDZ interacting domain (clear circle).
Vinothini Rajeeve (4257748) +9 more
core +1 more source
Scientific Reports, 2017 Cancer stem cells play an important role on tumor progression. Biomarkers of stem cell property and their relationship to extranodal involvement of malignant lymphocytes are undefined in diffuse large B-cell lymphoma (DLBCL).
Peng-Peng Xu +14 more
doaj +1 more source
Jurnal Teknologi dan Industri Pangan, 2015 Dragon fruit contains oligosaccharides, Including prebiotic ingredients, that are namely raffinose, stachyose, and fructo-oligosaccharides. The heat treatment process like jam producing can affect the functional properties of a food material.
Nurhayati, Gama Kusuma, Maryanto
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
JAM-C is internalised from junctions near the front of migrating cells.
, 2019 (A) JAM-C–GFPout was expressed in HUVECs, and the cells were allowed to form a confluent monolayer. The cell layer was scratched, and 45 min later, live-cell imaging was carried out with images acquired every 30 s for 45 min.
Vinothini Rajeeve (4257748) +9 more
core +1 more source
The International Journal of Biological Markers, 2019 Purpose: Aberrant expression of different tight junction proteins, including the junctional adhesion molecule-A (JAM-A), has been frequently reported in association with tumor progression of several malignancies. To our knowledge, this is the first study
Boljevic Ivana +5 more
doaj +1 more source
Indonesian Journal of Human Nutrition, 2018 Abstrak Antioksidan adalah zat yang dapat menangkal radikal bebas. Salah satu cara meningkatkan aktivitas antioksidan adalah dengan elisitasi dan perkecambahan.
Jaya Mahar Maligan +2 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source