Results 71 to 80 of about 38,224 (266)
Physiological Reports, 2017 Alcohol consumption promotes loss of intestinal barrier function. However, mechanisms by which ethanol affects the tight junction (TJ), the cellular structure responsible for maintaining the gut epithelial barrier, are not well understood.
Daniel M. Chopyk +5 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
JAM-A is a novel surface marker for NG2-Glia in the adult mouse brain
BMC Neuroscience, 2010 Background Junctional adhesion molecule-A (JAM-A) is an adhesive protein expressed in various cell types. JAM-A localizes to the tight junctions between contacting endothelial and epithelial cells, where it contributes to cell-cell adhesion and to the ...
Schwamborn Jens C +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
JFMR-Journal of Fisheries and Marine Research, 2020 Ikan kerapu sunu Plectropomus leopardus merupakan komoditas perikanan laut yang bernilai ekonomis tinggi dengan harga yang mahal. Benih telah dapat diproduksi mulai dipasarkan ukuran 3,0 cm, proses transportasi sangat diperlukan mengingat konsumen yang ...
Suko Ismi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Jamming of Semiflexible Polymers
Physical Review Letters, 2017 We study jamming in model freely rotating polymers as a function of chain length $N$ and bond angle $θ_0$. The volume fraction at jamming, $ϕ_J(θ_0)$, is minimal for rigid-rod-like chains ($θ_0 = 0$), and increases monotonically with increasing $θ_0 \leq π/2$.
openaire +4 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Jam-e Jam in Persian Literature
Bulletin of the Society for Near Eastern Studies in Japan, 1974 Jam-e Jam which means Jamshid's Cup, is one of the most traditional and favourite themes among the classical Persian poets. This Cup has been expressed in various names, such as Jam-e Kai Khosrou, Jam-e Jahan-numa, Jam-e Giti-numa, Jam-e Jahan-bin, Jam-e Alam-bin, Jam-e Jahan-ara, Jam-e Iskandar and Aine-ye Soleiman. Ferdousi, the greatest Persian epic
openaire +2 more sources