Results 101 to 110 of about 236,265 (247)
, 1958 Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about a large traffic jam in ...
WBAP-TV (Television station : Fort Worth, Tex.)
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Effectiveness of Cognitive-behavioral Therapy on the Psychological Security and Self-care Behaviors among Diabetes Patients [PDF]
Practice in Clinical PsychologyObjective: Type 2 diabetes mellitus (T2DM) is a chronic disease that increases the possibility of mental disorders due to physical problems. Therefore, psychological interventions such as diabetes self-care activities (DSCA) can probably create positive ...
Sima Farimanian, Mohammad Hossein Bayazi
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
JAM-C is ubiquitylated, and this governs its targeting to MVBs.
, 2019 (A) A schematic representation of the JAM-C–EGFPout construct showing all the lysine residues in the cytoplasmic tail that can be potentially modified by ubiquitylation and the JAM-C mutant generated.
Vinothini Rajeeve (4257748) +9 more
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
HYDRAULIC MODEL EXPERIMENTS ON ICE JAM OCCURRENCE CONSIDERING THE EFFECTS OF BRANCH RIVER JUNCTION [PDF]
, 2017 本研究は結氷河川におけるアイスジャム発生と河道形状の関係を明らかにすることを目的としている．水理模型実験を用いた既往研究では，河氷の速度，幅，厚さ，長さ，川幅の拡縮割合を用いてアイスジャムの規模を表し，アイスジャムによる河氷の速度の減衰割合を評価している．しかしながら，既往研究では支川合流の影響を考慮していない．本研究では支川合流を考慮した水理模型実験を行ない，アイスジャムの規模を表す値の適用性について検討した．さらに平面2次元不等流計算で算出したアイスジャムの規模を表す値から河氷速度の減衰割合を推定し，
岡部, 博一 +5 more
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
مجله علوم روانشناختی, 2020 Background: Numerous studies have compared the efficacy of cognitive therapy based on mindfulness awareness and reality therapy and cognitive emotion regulation. .
ziba EmamDoost +3 more
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