Comparison of computer-based cognitive stimulation efficacy with and without transcranial direct current stimulation (tDCS) on the quality of life of patients recovered from Covid-19 [PDF]
Background: Post-COVID-19 neurological sequelae may have a long-term negative impact on cognitive functions and quality of life in recovered patients.
Alireza Lotfi +2 more
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The Effectiveness of Emotion-Focused Therapy on Psychological Security in Women Involved in Domestic Violence [PDF]
Objective: The present investigation aimed to examine the efficacy of emotion-focused therapy in relation to the perception of psychological security and its components in women affected by domestic violence.
Tahereh Yarmohammadi +2 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Determinants of Capital Structure and Performance in Listed Companies of Tehran Stock Exchange [PDF]
This study examines the determinants of capital structure and performance in the listed companies of Tehran Stock Exchange. Information of the financial statements of the sample companies were extracted using Rahavardnovin Software.
Mina Jami, Amir Koloukhi
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Leukocyte attraction and transmigration in type 1 diabetes: neutralization of CXCR3 and JAM-C reduces the severity of disease [PDF]
Type 1 diabetes (T1D) is a chronic T cell-mediated autoimmune disorder that results in the destruction of insulin-producing pancreatic ß cells leading to life-long dependence on exogenous insulin. Attraction, activation and transmigration of inflammatory
Christen, Selina
core
Group exhibition by American curator Joan Backes. The seven artists selected in 'Vault Series: Jam II' are concerned with the ongoing engagement and expansion of abstraction and minimalism within ...
Jenkins, Kyle
core +1 more source
Ground-Water Quality in Islamkot and Mithi Talukas of District Tharparkar, Sindh, Pakistan
Surface water supplies are gradually becoming short in arid and semi-arid regions of the world. Thus, assessment of groundwater quality for crop use appears to be very essential for management and utilization of precious natural water resources.
Jhaman Das Suthar +4 more
doaj +1 more source

