Results 61 to 70 of about 236,265 (247)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Cube Jam (Engagement Innovation Project) [PDF]
, 2013 Cube Jam is a project developed in response to the new and rising marketing in large-scale interactive public screens - the Cube being a premier site.
Thomas, Lubi, Turner, Jane
core
JAM-C expression in lesion-free and atherosclerotic carotid arteries.
, 2016 (A) Carotid artery sections of 10-wk old, lesion-free (left panels) and 6-mths old atherosclerotic ApoE-/- mice (middle panels) stained for JAM-C and PECAM-1 expression.
Boris P. Lee (3149532) +8 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
JAM-C expression level regulates monocyte retention and rTEM.
, 2016 As observed in both animal models and human disease, levels of vascular JAM-C can be decreased or increased during inflammation. JAM-C expression above and below homeostatic levels increased rTEM of monocytes.
Boris P. Lee (3149532) +8 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
INFLUENCE OF ICE JAM AND RIVER NARROWING IN KENUFUCHI RIVER [PDF]
, 2019 On 9th March, 2018, due to unusual rainfall and temperature rise, ice jam occurred in the Kenufuchi River which has never been seen before. In the future, it is foreseen that water disaster will become more frequent with climate change, and rivers where ...
横山, 洋 +12 more
core
JAM-C is ubiquitylated by the E3 ligase CBL.
, 2019 (A–G) HUVECs were transfected with 2 different CBL siRNAs over a 96-h period. (A) Cells were lysed and analysed by SDS-PAGE and western blot, detecting CBL and tubulin. Knockdown was typically ≥90%. (B–E) Untreated or CBL knockdown cells were transfected
Vinothini Rajeeve (4257748) +9 more
core +1 more source
, 2020 BERPUASA selama 19 jam. Kedengarannya macam tidak percaya, tetapi itu yang dilalui sesetengah umat Islam terutama di benua Eropah yang berpuasa dalam tempoh amat ...
fazurawati, Che Lah
core +2 more sources
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source