Results 81 to 90 of about 1,015 (255)

m5C Reader ALYREF Promotes the Progression of Endometrial Cancer by Activating the XRCC6‐Mediated Wnt/β‐catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study identifies ALYREF as an oncogenic m5C reader in endometrial cancer. ALYREF recognizes NSUN2‐mediated m5C modification on XRCC6 mRNA to enhance transcript stability and increase XRCC6 expression. Elevated XRCC6 activates Wnt/β‐catenin signaling, resulting in accelerated tumor cell proliferation, migration, invasion, and xenograft tumor growth.
Linlin Hao   +8 more
wiley   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

open access: yesAdvanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao   +10 more
wiley   +1 more source

KEEPING IDENTITY, FREEDOM, AND INDEPENDENCE OF POLISH EXILES IN SIBERIA IN 19th CENTURY (TILL 1914) [PDF]

open access: yesRespectus Philologicus, 2015
First Poles were sent to Siberia to an exile as early as the second half of the 18th century to be followed by the participants of the Napoleonic campaign of 1812.
Wiesław Caban
doaj  

Designer Moiré Quantum Materials Enabled by Freestanding Oxide Membranes in Twisted and Hybrid Bilayers

open access: yesAdvanced Science, EarlyView.
Freestanding oxide membranes transform twistronics by enabling deterministic stacking, strain release, and integration with two‐dimensional materials. A unified framework links local atomic registry to structural reconstruction, polar textures, charge modulation, flat bands, and magnetic responses, while identifying the fabrication and characterization
Puneet Kaur, Rahul, Jan‐Chi Yang
wiley   +1 more source

Z rozważań nad społeczną i gospodarczą kondycją ziemiaństwa w Królestwie Polskim w okresie postyczniowego dziesięciolecia (1864–1874)

open access: yesPrace Historyczne
The subject of the article is the issue of widely understood social and economic aspects related to the history of the landed gentry in the Kingdom of Poland in the post-January decade.
Andrzej Przegaliński
doaj   +1 more source

(No) good practice in scientific research (on the Example of two Monographs about the Catholic Clergy in the 1863 Uprising and in Exile in Russia

open access: yesNasza Przeszłość
The text is not a classic review, but is a comparative confrontation of two scientific monographs published in 2002 and 2018. They touch on the participation of the Polish clergy in the January Uprising and their activities in Siberian exile.
Barbara Jędrychowska
doaj   +1 more source

Molecular Atlas of Key Food Odorants Reveals Mixture‐Level Organization and Enables Generative Aroma Design

open access: yesAdvanced Science, EarlyView.
KFO‐Atlas reveals how real‐world aromas are organized as structured mixtures rather than individual molecules. Building on these principles, KFO‐Gen, a generative AI framework, designs perceptually valid aroma formulations and reconstructs meat‐like aromas exclusively from plant‐derived odorants, providing a foundation for mixture‐level studies and AI ...
Jingzhi Zhang   +5 more
wiley   +1 more source

Religiosity of the prospective members of the Stańczycy group in their youth in comparison with their later religious views

open access: yesFolia Historica Cracoviensia
This article discusses the religious views of Stanisław Koźmian, Ludwik Wodzicki and Stanisław Tarnowski, as well as the shape of their piety before the January Uprising.
Mateusz Piotr Gancewski
doaj   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

open access: yesAdvanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li   +12 more
wiley   +1 more source

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