Results 51 to 60 of about 336,273 (367)
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Metallographic examination of four 7th–8th century long-blade weapons from Želovce (Slovakia)
Archeologické Rozhledy, 2018 The article presents the metallographic examination of three sabres and one double-edged sword coming from the 7th–8th century Slavic-Avar site of Želovce (Slovakia). All four weapons had been subjected to metallography as early as 1975, but the results
Jiří Hošek, Márk Haramza
doaj +1 more source
Phase diagram of Janus Particles [PDF]
, 2009 We deeply investigate a simple model representative of the recently synthesized Janus particles, i.e. colloidal spherical particles whose surface is divided into two areas of different chemical composition.
Achille Giacometti +3 more
core +1 more source
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Three dimensional Janus and time-dependent black holes
, 2007 We show that the three dimensional Janus geometry can be embedded into the type IIB supergravity and discuss its dual CFT description. We also find exact solutions of time dependent black holes with a nontrivial dilaton field in three and higher ...
Bak, Dongsu +2 more
core +1 more source
Matching microscopic and macroscopic responses in glasses [PDF]
, 2017 We first reproduce on the Janus and Janus II computers a milestone experiment that measures the spin-glass coherence length through the lowering of free-energy barriers induced by the Zeeman effect.
Baity-Jesi, M. +22 more
core +4 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Janus and Multifaced Supersymmetric Theories
, 2008 We investigate the various properties Janus supersymmetric Yang-Mills theories. A novel vacuum structure is found and BPS monopoles and dyons are studied. Less supersymmetric Janus theories found before are derived by a simpler method.
A. Clark +16 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Protein therapeutics have been considered a promising strategy for cancer treatment due to their highly specific bioactivity and few side effects. Unfortunately, the low physiological stability and poor membrane permeability of most protein drugs greatly
Shuting Zuo +3 more
doaj +1 more source