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What are Janus kinase (JAK) inhibitors?
Pediatric DermatologyJAK inhibitors are medications that can lower inflammation in the body. Some inflammation can help the body to fight infections or injuries. But too much inflammation is also the cause of certain skin problems. JAK inhibitors can help by lowering inflammation to improve skin diseases.
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[Janus kinase inhibitors for skin disorders].
Dermatologie (Heidelberg, Germany)Immune factors such as interferon‑ɣ and interleukin 4 belong to the group of cytokines that are dependent on type I/II receptors for their signal transmission. Upon activation, these receptors transmit their signal to the cell nucleus and, thus, modulate gene transcription via a signaling cascade consisting of Janus kinases (JAK).
Farzan, Solimani, Kamran, Ghoreschi
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Questioning the Janus Kinase (JAK) Inhibitors!
C59. POTRERO HILL: CASE REPORTS IN PULMONARY HYPERTENSION, 2022H. Hussain, S. Faryad, D. Taneja
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Treatment of renal cell carcinoma: Current status and future directions
Ca-A Cancer Journal for Clinicians, 2017Pedro Coelho Barata, Brian I Rini
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An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma
Nature, 2020Ugur Sahin, Petra Oehm, Mathias Vormehr
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Lung cancer: New biological insights and recent therapeutic advances
Ca-A Cancer Journal for Clinicians, 2011Suresh S Ramalingam, Fadlo R Khuri
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Phosphodiesterase-4 and Janus Kinase Inhibitors
2021Gillian Weston, Bruce Strober
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