Results 91 to 100 of about 5,587,857 (353)

Thoracic and cardiovascular surgery in Japan during 2014

General Thoracic and Cardiovascular Surgery, 2016
The Japanese Association for Thoracic Surgery has conducted annual surveys of thoracic surgery throughout Japan since 1986 to determine the statistics regarding the number of procedures according to operative category.
M. Masuda, M. Okumura, Y. Doki, S. Endo, Yasutaka Hirata, J. Kobayashi, H. Kuwano, N. Motomura, H. Nishida, Y. Saiki, A. Saito, H. Shimizu, F. Tanaka, K. Tanemoto, Y. Toh, H. Tsukihara, S. Wakui, H. Yokomise   +17 more
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Annual Report on the Environment in Japan

, 2008
This document reports the global and Japanese trends in creating a low carbon, material-cycle society.
Japan. Kankyōshō., Japan. Kankyōsho   +1 more
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The First Identification and Retrospective Study of Severe Fever With Thrombocytopenia Syndrome in Japan

Journal of Infectious Diseases, 2013
Background. Severe fever with thrombocytopenia syndrome (SFTS) is caused by SFTS virus (SFTSV), a novel bunyavirus reported to be endemic in central and northeastern China. This article describes the first identified patient with SFTS and a retrospective
Toru Takahashi, K. Maeda, Tadaki Suzuki, A. Ishido, T. Shigeoka, T. Tominaga, T. Kamei, M. Honda, D. Ninomiya, T. Sakai, T. Senba, Shozo Kaneyuki, S. Sakaguchi, A. Satoh, T. Hosokawa, Y. Kawabe, S. Kurihara, K. Izumikawa, S. Kohno, T. Azuma, K. Suemori, M. Yasukawa, T. Mizutani, T. Omatsu, Y. Katayama, M. Miyahara, Masahito Ijuin, Kazuko Doi, M. Okuda, Kazunori Umeki, Tomoya Saito, Kazuko Y. Fukushima, Kensuke Nakajima, T. Yoshikawa, H. Tani, S. Fukushi, A. Fukuma, M. Ogata, M. Shimojima, N. Nakajima, N. Nagata, H. Katano, Hitomi Fukumoto, Yuko Sato, H. Hasegawa, T. Yamagishi, K. Oishi, I. Kurane, S. Morikawa, M. Saijo   +49 more
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EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Environmental Impact Assessment in Japan [PDF]

This document introduces the definition of Environmental Impact Assessment (EIA), the EIA System in Japan, Japanese EIA Law and the Strategic Environmental ...
Japan. Kankyōshō.
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Synthesis Report on Observations, Projections, and Impact Assessments of Climate Change: Climate Change and Its Impacts in Japan [PDF]

, 2009
The Japan synthesis report includes causes of global warming, the current state and future of global warming, the impacts of and adaptation to climate change, and methodologies for observing and projecting climate change and ...
Japan. Kankyōshō., Japan Meteorological Agency, [Japan] Ministry of Education, Culture, Sports, Science and Technology   +2 more
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Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Demographic Change in Japan and the EU [PDF]

, 2010
This volume contains selected papers of the 2008 annual conference of the German Association for Social Science Research on Japan (Vereinigung für sozialwissenschaftliche Japanforschung e.V. – VSJF).

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