Results 101 to 110 of about 5,587,857 (353)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
The Christian movement in Japan.
, 1906 "Missionary directory--1907": p. [343]-398.Title-page in Japanese at end.1913-1914: "Including Korea and Formosa."Mode of access: Internet.Imprint varies: 1906-1910, The Standing Committee of Cooperating Christian Missions (Japan); 1911-1914, The ...
Conference of Federated Missions (Japan) +1 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Japan Update conference (2013- )
, 2019 The Japan Update is the flagship conference of the Australia-Japan Research Centre (AJRC) in Crawford School of Public Policy, and the Japan Institute at The Australian National University.
Australian National University. Japan Institute
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Adapting Live-Action Role-Play in Japan --How German Roots Do Not Destine Japanese Routes [PDF]
, 2019 [Replaying Japan 2019] 日時: 2019 年8月9日(金)-11日(日), 場所: 立命館大学衣笠キャンパス(創思館、存心館、以学館), 主催: 立命館大学ゲーム研究センターLive-action role-play (larp), a mixture of improv-theatre and role-playing game where participants interact physically as characters in a shared story ...
Björn-Ole, Kamm, Kamm, Björn-Ole
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continuum: Independent Animation from Japan and Australia
, 2023 This exhibition celebrates 15 vibrant and subtly subversive works of contemporary independent animation from filmmakers across Australia and Japan. The works featured in the collection seek to stand apart from mainstream animation, offering viewers a ...
Yano, H, Szapiro, D
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source