Results 101 to 110 of about 3,279,442 (393)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

An Optimal Investment Policy to Control the Land-based Water Pollutant into the Sea of Japan [PDF]

Northeast Asia countries (e.g. around the Sea of Japan area) cooperate in economic and environmental policies, etc., because the comprehensive problems like the climate change and global warming occur in recent years.
Katsuhiro Sakurai, Shintaro Kobayashi, Takeshi Mizunoya, Yoshiro Higano   +3 more
core  

Linking mantle upwelling with the lithosphere decent and the Japan Sea evolution: a hypothesis

Scientific Reports, 2013
Recent seismic tomography studies image a low velocity zone (interpreted as a high temperature anomaly) in the mantle beneath the subducting Pacific plate near the Japanese islands at the depth of about 400 km.
A. Ismail-Zadeh, S. Honda, I. Tsepelev
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

HISTORY OF PETER THE GREAT BAY DISCOVER AND OCEANOGRAPHIC SURVEYS IN THE JAPAN SEA TILL THE MIDDLE 20TH CENTURY

Известия ТИНРО, 2020
Peter the Great Bay (PGB) was not known to Europeans for a long time. The first European ship reached PGB in 1852. She was the French corvette Capricieuse commanded by captain G.
G. V. Khen
doaj   +1 more source

Areal distribution of water-insoluble particles in snow covers of the central mountainous area, Japan [PDF]

, 2012
The vertical snow samples collected from 6 locations (Iou-zen: 800m A.M.S.L; the nearest site from the Sea of Japan, Kongoudou-zan: 1300m, Nishi-Hodaka-Dake: 2200m; the Northern Japan Alps, Hachimori-yama: 2100m, Kiriga-mine: 2000m, Yatsuga-take: 2200m ...
Kawada, Kunio, Matsumoto, Ena, Satake, Hiroshi, Toyama, Kazuhiro   +3 more
core  

Comment [on "Origin of the Chichibu Sea, Japan: Middle Paleozoic to Early Mesozoic plate construction in the northern margin of the Gondwana continent" by S. Otoh, S. Yamakita, and S. Yanai] [PDF]

, 1992
International audienceComment [on "Origin of the Chichibu Sea, Japan: Middle Paleozoic to Early Mesozoic plate construction in the northern margin of the Gondwana continent" by S. Otoh, S.
Caridroit, Martial, Charvet, Jacques, Faure, Michel   +2 more
core   +3 more sources

Results of fishery for pink salmon Oncorhynchus gorbuscha in Primorye Region and hydrometeorological conditions in the Japan Sea in 2023

Известия ТИНРО
Catch and distribution of pink salmon in the Primorye fishing subzone are compared for 2000–2023. Dynamics of the spawning run of pink salmon in 2023 is considered in detail.
A. V. Lysenko, A. A. Nikitin, Т. A. Shatilina, E. I. Barabanshchikov   +3 more
doaj   +1 more source

STRUCTURE AND DISTRIBUTION OF MACROBENTHOS IN THE SUBLITTORAL ZONE OF THE VLADIMIR BAY, JAPAN SEA

Известия ТИНРО, 2018
Bottom substrates and structure and distribution of macrobenthos in the sublittoral zone of the Vladimir Bay (northwestern Japan Sea) were surveyed in July 2012 and 2014. The substrates were identified and their spatial patterns were described.
Yu. A. Galysheva, U. I. Serdyuk, N. K. Khristoforova   +2 more
doaj   +1 more source