Results 81 to 90 of about 4,267,043 (286)

Fishes of the Hibiki-nada Sea and Mi-shima island, Yamaguchi Prefecture, Japan [PDF]

, 2018
An annotated checklist of the marine fishes of the Hibiki-nada Sea and Mi-shima island, Yamaguchi Prefecture, Japan, was compiled on the basis of 382 specimens.
藤原, 恭司, Nagai, Setsuko, オカダ, ショウヘイ, Motomura, Hiroyuki, Okada, Shohei, Fujiwara, Kyoji, 毛利, 雅彦, Mohri, Masahiko, 田上, 英明, 1215, 永井, 節子, 本村, 浩之, モウリ, マサヒコ, 10416464, 鎌野, 忠, 40601084, ハタ, カズヒロ, 岡田, 翔平, 秦, 一浩, ナガイ, セツコ, Tanoue, Hideaki, タノウエ, ヒデアキ, フジワラ, キョウジ, カマノ, タダシ, Hata, Kazuhiro, モトムラ, ヒロユキ, Kamano, Tadashi, 948, 1208   +28 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Seasonal Change of the Size Distribution and Generation Length of the Chaetognath Sagitta elegans in the Japan Sea: Arctic Characteristics at a Temperate Latitude

, 1997
Analysis of the size frequency distributions of Sagitta elegans from Yamato Tai in the central Japan Sea during 1993 to 1995, shows that the arrow worm has a life span of two years.
583, 西濱, 士郎, 50372024, Hirakawa, Kazumasa, 1940, ニシハマ, シロウ, ヒラカワ, カズマサ, Nishihama, Shiro, 40372015, 平川, 和正   +9 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Possible northern persistence of Siebold's beech, Fagus crenata, at its northernmost distribution limit on an island in Japan Sea: Okushiri Island, Hokkaido. [PDF]

Front Plant Sci, 2022
Kitamura K, Namikawa K, Tsuda Y, Kobayashi M, Matsui T.   +4 more
europepmc   +1 more source

Spatial Variation in Growth of Japanese Common Squid, Todarodes pacificus STEENSTRUP in the Sea of Japan

, 1996
Relationship between body size and age of Japanese common squid, Todarodes pacificus STEENSTRUP which were caught by squid jigging in the Sea of Japan from late June to early July 1994 was examined.
478, 0000-0001-9908-2410, ヒヤマ, ヨシアキ, Kidokoro, Hideaki, 601, Hiyama, Yoshiaki, 檜山, 義明, 木所, 英昭, 30371975, キドコロ, ヒデアキ, 50371894   +10 more
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Weakened pacific overturning circulation, winter monsoon dominance and tectonism re-organized Japan Sea paleoceanography during the Late Miocene global cooling. [PDF]

Sci Rep, 2022
Matsuzaki KM, Ikeda M, Tada R.
europepmc   +1 more source

Growth of the Japanese Common Squid Todarodes pacificus in the Sea of Japan in 1996 Analyzed from Statolith Microstructure

, 1999
Growth of the Japanese common squid Todarodes pacificus caught in the Sea of Japan in 1996 was examined from statolith microstructure analysis. Specimens were taken by set nets in Wakasa Bay from March to May, and caught by squid jiggers set on research ...
和田, 洋藏, Shikata, Takafumi, 0000-0001-9908-2410, Kidokoro, Hideaki, キドコロ, ヒデアキ, Sano, Katsuo, 50371894, ワダ, ヨウゾウ, Wada, Yozo, 478, 木所, 英昭, シカタ, タカフミ, 佐野, 勝雄, サノ, カツオ, ウジ, リョウスケ, 四方, 崇文, 氏, 良介, Uji, Ryosuke   +17 more
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source