Results 111 to 120 of about 652,978 (305)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Quaternary Research (Daiyonki-Kenkyu), 1990 This is a summary of the presidential address to the public at the 19th annual meeting of the Japanese Association for Quaternary Research, held at Tottori August 18-20, 1989. The address had two parts: one was an introduction to the concept of “Quaternary” and the significance of Quaternary research, and the other was an elucidation of the discussion ...
openaire +2 more sources
Search for lepton flavor violation via the intense high-energy muon beam
, 2004 A deep inerastic scattering process \mutau is discussed to study lepton flavor violation between muons and tau leptons. In supersymmetric models, the Higgs boson mediated diagrams could be important for this reaction.
Abe +14 more
core +2 more sources
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Известия ТИНРО, 2019 Current state of the mussel Crenomytilus grayanus stock in the coastal waters of Primorsky Region (Japan Sea) is considered on the base of diving surveys conducted in 2007–2018.
L. G. Sedova, D. A. Sokolenko
doaj +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Lagrangian study of transport and mixing in a mesoscale eddy street
, 2011 We use dynamical systems approach and Lagrangian tools to study surface transport and mixing of water masses in a selected coastal region of the Japan Sea with moving mesoscale eddies associated with the Primorskoye Current.
Budyansky, M. V. +3 more
core +1 more source
FEBS Open Bio, EarlyView.NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source