The Straits of Malacca: Regional powers vis-a-vis littoral states in strategic and security issues and interests [PDF]
This paper presents an overview of the strategic and security issues surrounding the Straits of Malacca. It begins by introducing the strategic nature of the Straits of Malacca and piracy threat in the busy sea lane. Subsequently this paper discusses the
Ismail, Siti Zubaidah +1 more
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
The Ariake Sea located in the west parts of Kyushu Island is a semi-closed and macro-tidal shallow sea, and has the largest tidal flat in Japan. A large mud tidal flat with a productive ecosystem found along the western shoreline of the sea makes this ...
ALIM ISNANSETYO +3 more
doaj +1 more source
Evolution of mixing state of black carbon particles: Aircraft measurements over the western Pacific in March 2004 [PDF]
We report the evolution of the mixing state of black carbon (BC) particles in urban plumes measured by an airborne single particle soot photometer. The aircraft observations were conducted over the ocean near the coast of Japan in March 2004.
Blake, DR +9 more
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The Delimitation of East China Sea Continental Shelf:Sino-Japanese Disputes from the Perspective of International Law [PDF]
The East China Sea which covers a total area of 750,000 square kilometers is a semi-closed sea lying between the eastern coast of Chinas mainland and the Pacific Ocean, bounded on the west by China, on the east by the Kyushu and the Ryukyu Islands of ...
Zhu Fenglan
core +1 more source
Snailfishes of the Careproctus rastrinus complex (Liparidae): redescriptions of seven species in the North Pacific Ocean region, with the description of a new species from the Beaufort Sea. [PDF]
Herein we review and recognize as valid all previously described species of the Careproctus rastrinus complex based on morphological evidence, provide diagnoses and descriptions of all species, describe a new species from the Beaufort Sea, and address ...
Kai, Yoshiaki +2 more
core +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peter the Great Bay (PGB) was not known to Europeans for a long time. The first European ship reached PGB in 1852. She was the French corvette Capricieuse commanded by captain G.
G. V. Khen
doaj +1 more source
An Optimal Investment Policy to Control the Land-based Water Pollutant into the Sea of Japan [PDF]
Northeast Asia countries (e.g. around the Sea of Japan area) cooperate in economic and environmental policies, etc., because the comprehensive problems like the climate change and global warming occur in recent years.
Katsuhiro Sakurai +3 more
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