Results 61 to 70 of about 1,347,749 (178)

Prophylactic and therapeutic vaccines for Japanese cedar pollinosis

Folia Pharmacologica Japonica, 2010
スギ花粉症は日本固有の季節性アレルギー疾患で，くしゃみや鼻炎症状，結膜炎症状を特徴とする．その患者数は3000万人を超えたとも言われている．症状の軽い人は，抗ヒスタミン薬や抗ロイコトリエン薬の服用で症状をある程度コントロールすることができるものの，中重症度の多くの患者さんは，既存の対症療法に満足していないのが実情で，根本的な治療法が求められている．しかしながら，現在唯一の治療法はスギ花粉エキスを皮下投与する減感作療法であるが，十分に普及していない．その主たる理由して，長期間の通院が必要であることや作用機序が十分に解明されていないこと，さらにはアナフィラキシーを誘発する危険性を回避するために，高容量のスギ花粉エキスを注射できないことが挙げられる．我々は，現状の問題を解決する新たな予防・治療法として ...
openaire   +3 more sources

Major Basic Protein, Eosinophil Cationic Protein, and Arylsulfatase in Nasal Secretions of Patients with Japanese Cedar Pollinosis [PDF]

, 1995
In 15 patients with Japanese cedar pollinosis and 10 healthy control subjects, levels of major basic protein (MBP), eosinophil cationic protein (ECP), and arylsulfatase B (As) in the nasal secretions were examined before and after challenge with Japanese
Saito, Chisato, Nishioka, Satoko, Masuda, Yu, Nishioka, Keiko, Ogawa, Teruhiro, Nakagawa, Fumio, Ohomichi, Takuya   +6 more
core   +1 more source

The impact of COVID‐19 on hay fever treatment in Japan: A retrospective cohort study based on the Japanese claims database

Clinical and Translational Allergy, Volume 14, Issue 9, September 2024.
Abstract Background Hay fever (HF) presents with various symptoms, including allergic conjunctivitis and rhinitis, and requires cross‐organ treatment. This study assessed the impact of the coronavirus disease 2019 (COVID‐19) pandemic on HF treatment trends.
Yasutsugu Akasaki, Takenori Inomata, Masao Iwagami, Jaemyoung Sung, Ken Nagino, Takeya Adachi, Hideaki Morita, Mayumi Tamari, Keigo Kainuma, Keiko Kan‐o, Hiroaki Ogata, Masafumi Sakashita, Masaki Futamura, Yosuke Kurashima, Saeko Nakajima, Katsunori Masaki, Yasushi Ogawa, Sakura Sato, Akihiro Miyagawa, Akie Midorikawa‐Inomata, Keiichi Fujimoto, Yuichi Okumura, Kenta Fujio, Tianxiang Huang, Kunihiko Hirosawa, Yuki Morooka, Akira Murakami, Shintaro Nakao   +27 more
wiley   +1 more source

Climate change from the Asia‐Pacific perspective: What an allergist needs to know and do

Pediatric Allergy and Immunology, Volume 35, Issue 8, August 2024.
Abstract Allergic diseases such as asthma, atopic dermatitis, and food allergies are a burgeoning health challenge in the Asia‐Pacific region. Compounding this, the region has become increasingly susceptible to the impacts of climate change. The region has weathered extreme precipitation, intense heat waves, and dust storms over the recent decades ...
Amanda Zain, Inez Yeo, Lydia Wong, Lynette P. Shek   +3 more
wiley   +1 more source

Effect of Japanese Cedar Pollen Sublingual Immunotherapy on Asthma Patients with Seasonal Allergic Rhinitis Caused by Japanese Cedar Pollen

Biomolecules, 2022
Allergen immunotherapy is a promising treatment for allergic diseases that induce immune tolerance through the administration of specific allergens. In this study, we investigate the efficacy of sublingual immunotherapy (SLIT) in asthmatic patients with ...
Shoko Ueda, Jun Ito, Norihiro Harada, Sonoko Harada, Hitoshi Sasano, Yuuki Sandhu, Yuki Tanabe, Sumiko Abe, Satomi Shiota, Yuzo Kodama, Tetsutaro Nagaoka, Fumihiko Makino, Asako Chiba, Hisaya Akiba, Ryo Atsuta, Sachiko Miyake, Kazuhisa Takahashi   +16 more
doaj   +1 more source

Roles of omalizumab in various allergic diseases

Allergology International, 2020
IgE and mast cells play a pivotal role in various allergic diseases, including asthma, allergic rhinitis, and urticaria. Treatment with omalizumab, a monoclonal anti-IgE antibody, has significantly improved control of these allergic diseases and ...
Yoshimichi Okayama, Hisako Matsumoto, Hiroshi Odajima, Shunsuke Takahagi, Michihiro Hide, Kimihiro Okubo   +5 more
doaj   +1 more source

Comparison of sensitization and prevalence of Japanese cedar pollen and mite-induced perennial allergic rhinitis between 2006 and 2016 in hospital workers in Japan

Allergology International, 2021
Background: The prevalence of allergic rhinitis (AR) is increasing worldwide, mainly due to an increase in antigen exposure. We conducted an epidemiological study involving the staff of the University of Fukui Hospital and its associated hospital in 2006.
Masafumi Sakashita, Toshiki Tsutsumiuchi, Seita Kubo, Takahiro Tokunaga, Tetsuji Takabayashi, Yoshimasa Imoto, Yuji Kato, Kanako Yoshida, Yukihiro Kimura, Yukinori Kato, Masafumi Kanno, Kazuhiro Ogi, Masayuki Okamoto, Norihiko Narita, Shigeharu Fujieda   +14 more
doaj   +1 more source

Analysis of Factors Associated with Cedar Pollen Sensitization and Development of Pollinosis in a Young Japanese Adult Population [PDF]

, 2018
三重大学博士(医学)application/pdfMethods:Subjects were 382 young adult volunteers who completed a self-administered questionnaire on self-reported subjective symptoms of pollinosis, physician-diagnosed pollinosis, and background factors.
Nakamura, Satoshi, 中村, 哲, ナカムラ, サトシ   +2 more
core  

Supplemental material for Evaluation of Montelukast for the Treatment of Children With Japanese Cedar Pollinosis Using an Artificial Exposure Chamber (OHIO Chamber)

, 2018
Supplemental material for Evaluation of Montelukast for the Treatment of Children With Japanese Cedar Pollinosis Using an Artificial Exposure Chamber (OHIO Chamber) by Kazuhiro Hashiguchi, Kimihiro Okubo, Yoichi Inoue, Hirotaka Numaguchi, Kumi Tanaka ...
Chisato Nishida (3124581), Yoichi Inoue (3124572), Anish Mehta (3124566), George Philip (3124563), Kazuhiro Hashiguchi (1546492), Kimihiro Okubo (3124569), Hirotaka Numaguchi (3124575), Kumi Tanaka (3124578), Itori Saito (3124560), Nobuyuki Oshima (3124584)   +9 more
core   +1 more source

Transcutaneous Delivery of Immunomodulating Pollen Extract-Galactomannan Conjugate by Solid-in-Oil Nanodispersions for Pollinosis Immunotherapy

Pharmaceutics, 2019
Japanese cedar pollinosis is a type I allergic disease and has already become a major public health problem in Japan. Conventional subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) cannot meet patients’ needs owing to the side ...
Qingliang Kong, Kouki Higasijima, Rie Wakabayashi, Yoshiro Tahara, Momoko Kitaoka, Hiroki Obayashi, Yanting Hou, Noriho Kamiya, Masahiro Goto   +8 more
doaj   +1 more source