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Japanese Encephalitis Vaccines. [PDF]

Curr Treat Options Infect Dis, 2020
As an eminently vaccine-preventable disease, encephalitis caused by Japanese encephalitis virus (JEV) has attracted an unusually high degree of attention from those seeking to develop viral vaccines. Since the 1950s, all types of JEV vaccines including inactivated, recombinant and live attenuated ones have been licensed.
Satchidanandam V.
europepmc   +5 more sources

Safety of Japanese encephalitis vaccines [PDF]

Human Vaccines & Immunotherapeutics, 2021
Japanese encephalitis (JE) is an endemic disease dominantly in the Asia-Pacific region with mortality rate varying between 3% and 30%. Long-term neuropsychiatric sequelae developed in 30–50% of the survivors.
Ya-Li Hu, Ping-Ing Lee
doaj   +5 more sources

Japanese encephalitis vaccines: Immunogenicity, protective efficacy, effectiveness, and impact on the burden of disease [PDF]

Human Vaccines & Immunotherapeutics, 2017
Japanese encephalitis (JE) is a serious public health concern in most of Asia. The disease is caused by JE virus (JEV), a flavivirus transmitted by Culex mosquitoes.
Nagendra R. Hegde, Milind M. Gore
doaj   +4 more sources

Japanese Encephalitis Vaccines. [PDF]

J Bioterror Biodef, 2011
Japanese encephalitis (JE) is a significant human health concern in Asia, Indonesia and parts of Australia with more than 3 billion people potentially at risk of infection with Japanese encephalitis virus (JEV), the causative agent of JE. Given the risk to human health and the theoretical potential for JEV use as a bioweapon, the development of safe ...
McArthur MA, Holbrook MR.
europepmc   +4 more sources

Partial protective efficacy of the current licensed Japanese encephalitis live vaccine against the emerging genotype I Japanese encephalitis virus isolated from sheep [PDF]

Frontiers in Immunology
IntroductionVaccination remains the most effective strategy for preventing and controlling Japanese encephalitis (JE). The Japanese encephalitis virus (JEV) seroconversion has been documented in sheep and goats across various countries, with occasional ...
Hailong Zhang, Yan Zhang, Dan Li, Jiayang Zheng, Junjie Zhang, Zongjie Li, Ke Liu, Beibei Li, Donghua Shao, Yafeng Qiu, Zhiyong Ma, Jianchao Wei, Juxiang Liu   +12 more
doaj   +4 more sources

Immunogenicity, immune persistence, and safety of japanese encephalitis vaccine schedules among adults in Ningxia, China [PDF]

npj Vaccines
Live attenuated and vero-cell-inactivated Japanese Encephalitis vaccines (LJEV, IJEV) have been in common use in young children in China since 1989 and 2004, associated with large reductions in Japanese encephalitis (JE) incidence.
Dan Wu, Qikai Yin, Ying Zhang, Yixing Li, Liwei Zhou, Shihong Fu, Xue Li, Hui Zheng, Yiqun Wu, Luping Zhou, Qian Zhang, Mingshuang Li, Tingting Yan, Xueying Qin, Lance Rodewald, Junhui Wu, Yanru Sun, Zhijie An, Zundong Yin, Huanyu Wang, Yonghua Hu   +20 more
doaj   +2 more sources

The hidden threats posed by Japanese encephalitis virus genotype V [PDF]

Journal of Virology
Japanese encephalitis virus (JEV) remains a major cause of viral encephalitis in Asia. Among its five genotypes (GI–GV), genotype V (GV) has re-emerged and become the predominant lineage in mosquitoes in the Republic of Korea, with sporadic human cases ...
Qi Li, Hridesh Mishra, Kevin C. Kain, Ran Wang   +3 more
doaj   +2 more sources

Advances and Challenges in Vaccination and Therapeutic Strategies Against Japanese Encephalitis Virus [PDF]

Pathogens
The Japanese encephalitis virus (JEV) remains a major cause of viral encephalitis in Asia, and recent epidemiological shifts driven by the predominance of genotype I and the re-emergence of genotype V have renewed concerns regarding control efforts ...
Jae-Yeon Park, Hye-Mi Lee
doaj   +2 more sources

Immunogenicity and Safety of Pneumococcal Vaccines Co-Administered with Common Travel Vaccines in Adults: A Systematic Review [PDF]

Vaccines
Background: Co-administration of vaccines can impact the immune response and safety. We aim to systematically review the current scientific literature and find evidence regarding the immunogenicity and safety of pneumococcal vaccines co-administered with
Raziyeh Niyati, Omid Rezahosseini, Christina Ekenberg, Carsten Schade Larsen, Zitta Barrella Harboe   +4 more
doaj   +2 more sources

Epidemiology of Japanese encephalitis in the Philippines prior to routine immunization

International Journal of Infectious Diseases, 2021
Background: Findings were published in 2015 that highlighted the endemicity of Japanese Encephalitis (JE) in the Philippines. The policymakers responded by conducting an immunization campaign and strengthening the surveillance system.
Anna Lena Lopez, Peter Francis Raguindin, Josephine G. Aldaba, Ferchito Avelino, Ava Kristy Sy, James D. Heffelfinger, Maria Wilda T. Silva   +6 more
doaj   +1 more source