Results 51 to 60 of about 10,595 (215)

Japanese encephalitis virus live attenuated vaccine strains display altered immunogenicity, virulence and genetic diversity

npj Vaccines, 2021
Japanese encephalitis virus (JEV) is the etiological agent of Japanese encephalitis (JE). The most commonly used vaccine used to prevent JE is the live-attenuated strain SA14-14-2, which was generated by serial passage of the wild-type (WT) JEV strain ...
Emily H. Davis, Andrew S. Beck, Li Li, Mellodee M. White, Marianne Banks Greenberg, Jill K. Thompson, Steven G. Widen, Alan D. T. Barrett, Nigel Bourne   +8 more
doaj   +1 more source

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

Advanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez, Julio García‐Cordero, Gabriela Navarro‐Tovar, Leticia Cedillo‐Barrón   +3 more
wiley   +1 more source

Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus

mBio, 2018
Japanese encephalitis virus (JEV) remains a leading cause of viral encephalitis worldwide. Although JEV-specific antibodies have been described, an assessment of their ability to neutralize multiple genotypes of JEV has been limited.
Estefania Fernandez, Nurgun Kose, Melissa A. Edeling, Jagat Adhikari, Gopal Sapparapu, Susana M. Lazarte, Christopher A. Nelson, Jennifer Govero, Michael L. Gross, Daved H. Fremont, James E. Crowe, Michael S. Diamond   +11 more
doaj   +1 more source

Infant Botulism: A Case Study in Integrated Clinical and Public Health Response

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Early recognition of constipation, feeding difficulty, and descending weakness in infants is vital for prompt diagnosis of infant botulism. Bedside nerve studies support early treatment. Rapid public health notification and coordinated access to specific therapies, including timely use of BAT and BIG‐IV, are essential to optimize outcomes and ...
John Gannon, Tiarnán Fallon Verbruggen, Sinéad Burke, Leah Loughlin, Cally Brits, Kara Tedford, John C. McHugh, Huw Mayberry, Mary O'Regan, Bridget Freyne, Niall Conroy   +10 more
wiley   +1 more source

Clinical progress note: Varicella Zoster

Journal of Hospital Medicine, Volume 20, Issue 12, Page 1348-1350, December 2025.
Abstract Varicella Zoster virus (VZV) is the etiologic agent responsible for varicella and herpes zoster (shingles). Nonimmune children and adults acutely infected with VZV typically experience a vesicular and pruritic rash that progresses from the face and trunk and generalizes to the extremities, accompanied by an oral enanthem along with symptoms of
Sirey Zhang, Adam L. Hersh, T. W. Jones
wiley   +1 more source

Systematic Review of Postvaccination Ocular Adverse Events: A Comprehensive Analysis of Published Reports

Journal of Medical Virology, Volume 97, Issue 12, December 2025.
ABSTRACT Ocular adverse events following COVID‐19 vaccination are well described; however, systematic analyses of non‐COVID antiviral vaccines remain limited. This review aimed to evaluate ocular complications associated with non‐COVID antiviral immunizations, including influenza, varicella‐zoster (VZV), human papillomavirus (HPV), and hepatitis B (HBV)
Yaru Zou, Koju Kamoi, Yuan Zong, Jing Zhang, Mingming Yang, Kyoko Ohno‐Matsui   +5 more
wiley   +1 more source

Insect-specific virus platforms for arbovirus vaccine development

Frontiers in Immunology
Certain insect-specific viruses (ISVs), specifically the mosquito alphaviruses, Eilat and Yada Yada viruses, and orthoflaviviruses, Binjari, Aripo, YN15-283-02 and Chaoyang viruses, have emerged as potential platforms for generation of whole virus ...
Roy A. Hall, Roy A. Hall, Wilson Nguyen, Alexander A. Khromykh, Alexander A. Khromykh, Andreas Suhrbier, Andreas Suhrbier   +6 more
doaj   +1 more source

Polyethylene Glycol‐Functionalized Graphene Oxide Nanocomposites: Advances in Biomedical Applications

Nano Select, Volume 6, Issue 12, December 2025.
Polyethylene glycol‐functionalized graphene oxide (PEG‐GO) nanocomposites revolutionize nanomedicine with their high surface area and tunable properties. This review explores their synthesis, characterization, and applications in drug delivery, gene therapy, biosensing, and photothermal therapy.
Oluwasegun Chijioke Adekoya, Gbolahan Joseph Adekoya, Williams Kehinde Kupolati, Yskandar Hamam, Rotimi Emmanuel Sadiku   +4 more
wiley   +1 more source

Efficacy and safety of anifrolumab across organ domains of systemic lupus erythematosus: A systematic review and meta‐analysis

Rheumatology &Autoimmunity, Volume 5, Issue 4, Page 285-296, December 2025.
A systematic review and meta‐analysis were conducted to review all clinical trial results of anifrolumab for treating systemic lupus erythematosus. Fourteen studies were included comprising 1322 patients and five studies were meta‐analyzed. It was found that anifrolumab 300 mg IV led to clinical improvement across composite lupus scores, cutaneous ...
Yomna W. Mahmoud, Mohamed Ramadan S., Doaa Radwan G., Mariam S. Abdulhafiz, Yassin M. El‐Shnawy, Alaa Alaa H., Sara Naser Sebie, Maryam A. Elashmawi, Husni Zahi M., Mohammad T. Abuawwad, Mohammad J. Taha, Abdulqadir J. Nashwan   +11 more
wiley   +1 more source

Research progress of mosquito-borne virus mRNA vaccines

Molecular Therapy: Methods & Clinical Development
In recent years, mRNA vaccines have emerged as a leading technology for preventing infectious diseases due to their rapid development and high immunogenicity.
Ningze Sun, Zhiwei Su, Xiaoyan Zheng
doaj   +1 more source