Results 61 to 70 of about 24,040 (189)

Change in Japanese Encephalitis Virus Distribution,Thailand

open access: yesEmerging Infectious Diseases, 2008
Les génotypes abstraits du virus de l'encéphalite japonaise (VEJ) en Thaïlande ont été étudiés chez des porcs et des moustiques collectés près des maisons de cas humains confirmés de VEJ en 2003–2005. Douze souches de JEV isolées appartenaient au génotype I, ce qui montre un changement par rapport à l'incidence du génotype III qui a commencé dans les ...
Narong Nitatpattana   +7 more
openaire   +4 more sources

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 8, Page 1591-1601, August 2026.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

open access: yesAdvanced Science, Volume 13, Issue 44, 7 August 2026.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth   +10 more
wiley   +1 more source

Coltiviruses and Seadornaviruses in North America, Europe, and Asia

open access: yesEmerging Infectious Diseases, 2005
Coltiviruses are tickborne viruses of the genus Coltivirus. The type species, Colorado tick fever virus (from North America), has been isolated from patients with flulike syndromes, meningitis, encephalitis, and other severe complications.
Houssam Attoui   +3 more
doaj   +1 more source

The Neuroprotective Potentials of Dual GIP/GLP1‐RA (Tirzepatide): From Preclinical Experiments to Clinical Trials: A Scoping Review

open access: yesBrain and Behavior, Volume 16, Issue 8, August 2026.
The graphical abstract summarizes the current evidence on the potential neuroprotective effects of tirzepatide (TZP), a dual GIP/GLP‐1 receptor agonist, across mechanistic, preclinical, and clinical domains. Mechanistically, TZP is proposed to exert direct neural effects, preserve mitochondrial function, reduce apoptosis, oxidative stress, and ...
Yousef Hawas   +6 more
wiley   +1 more source

Active Vaccination Strategies for Alzheimer's Disease: An Expanded Review

open access: yesEuropean Journal of Immunology, Volume 56, Issue 8, August 2026.
Overview of immunotherapeutic strategies targeting Alzheimer's disease (AD) pathology and their clinical implications. (Left) Key neuropathological hallmarks of AD, including extracellular amyloid‐beta (Aβ) aggregates and intraneuronal hyperphosphorylated Tau (phospho‐Tau), converge to produce synaptic failure, neuroinflammation and neuronal ...
Antonella Comitato   +2 more
wiley   +1 more source

Incongruence between confirmed and suspected clinical cases of Japanese encephalitis virus infection

open access: yesFrontiers in Cellular and Infection Microbiology
BackgroundJapanese encephalitis (JE) is a notifiable infectious disease in China. Information on every case of JE is reported to the superior health administration department.
Wei Li   +11 more
doaj   +1 more source

Antibody Responses in Pediatric Dengue Indicate Emergence and Co‐Circulation of DENV‐3 Genotypes I and III in Myanmar and Orthoflavivirus Cross‐Reactivity

open access: yesJournal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Dengue virus (DENV) remains a major public health concern in Southeast Asia, disproportionately affecting children. In Myanmar, DENV‐3 Genotype III predominated before 2017, with Genotype I emerging thereafter. To assess the impact of this emergence on antibody responses, we analyzed paired acute and convalescent serum samples from 38 ...
Jean Claude Balingit   +11 more
wiley   +1 more source

Metagenomic sequencing reveals viral diversity of mosquitoes from Shandong Province, China

open access: yesMicrobiology Spectrum
Mosquitoes carry a large number of known and unknown viruses, some of which could cause serious diseases in humans or animals. Metagenomic sequencing for mosquito viromes is crucial for understanding the evolutionary history of viruses and preventing ...
Yuhao Wang   +9 more
doaj   +1 more source

Associations of Inherited Chromosomally‐Integrated Human Herpesvirus 6 With Dementia Incidence, Inflammation, and Other Dementia Risk Factors in the UK Biobank

open access: yesJournal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT The infection theory of dementia states that viral infections and chronic inflammation play a role in its pathogenesis. We aimed to test whether testing positive for inherited chromosomally‐integrated human herpesvirus 6 (iciHHV‐6) is associated with an increased dementia incidence, inflammation, and other dementia risk factors. We included n =
Zhong Qiya   +5 more
wiley   +1 more source

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