Results 81 to 90 of about 108,229 (284)

CSF‐Compartmentalized Antibody Glycoprofiles in NMDAR Encephalitis Associate with Etiology and Functional Recovery

Annals of Neurology, EarlyView.
Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo, Claudia Papi, Chiara Milano, Esther Aguilar, Estibaliz Maudes, Ivana Duvnjak Orešković, Jerko Štambuk, Maja Pučić‐Baković, Gemma Olivé‐Cirera, Elianet Fonseca, Mar Guasp, Eugenia Martinez‐Hernandez, Helena Ariño, Takahiro Iizuka, Thais Armangué, Josep Dalmau, Marianna Spatola   +16 more
wiley   +1 more source

Emergence or improved detection of Japanese encephalitis virus in the Himalayan highlands? [PDF]

, 2016
The emergence of Japanese encephalitis virus (JEV) in the Himalayan highlands is of significant veterinary and public health concern and may be related to climate warming and anthropogenic landscape change, or simply improved surveillance. To investigate
Barker, Christopher M, Baylis, Matthew, Caminade, Cyril, Impoinvil, Daniel E, Joshi, Bhoj R, Pant, Ganesh R, Rayamajhi, Ajit, Reisen, William K   +7 more
core   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Outbreak of West Nile Virus Infection in Kerala

RGUHS Journal of Medical Sciences
West Nile virus infection may present as encephalitis and is transmitted through the bite of an infected mosquito.
P S Shankar
doaj   +1 more source

Temperature-sensitive mutants of Japanese encephalitis virus [PDF]

Journal of Virology, 1985
Ten stable temperature-sensitive mutants of Japanese encephalitis virus were isolated after mutagenesis by growth of cloned wild-type virus in the presence of the nucleic acid precursor analogs 5-fluorouracil and 5-azacytidine. Mutants were selected which grew at least 100-fold better at 33 degrees C than at 41 degrees C.
P S, Eastman, C D, Blair
openaire   +2 more sources

Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability

Nature Communications, 2017
Although several different flaviviruses may cause encephalitis, Japanese encephalitis virus is the most significant, being responsible for thousands of deaths each year in Asia.
Xiangxi Wang, Shihua Li, Ling Zhu, Qinggong Nian, S. Yuan, Q. Gao, Zhong-yu Hu, Qing Ye, Xiao-Feng Li, Dong-Yang Xie, N. Shaw, Junzhi Wang, T. Walter, J. Huiskonen, E. Fry, C. Qin, D. Stuart, Z. Rao   +17 more
semanticscholar   +1 more source

Anti‐NMDA receptor autoimmune encephalitis associated with ovarian teratoma: A case series and literature review

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 23-30, April 2025.
Abstract Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra‐limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti‐NMDA (N‐methyl‐D‐aspartate) receptor encephalitis was first described in 2007
Pham Ba Nha, Nguyen Phuong Tu, Nguyen Viet Ha, Duong Thi Thu Hien, Nguyen Thi Thu Phuong, Nguyen Anh Son, Nguyen Tien Hoang   +6 more
wiley   +1 more source

Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein

PLoS Pathogens, 2018
CCCH-type zinc-finger antiviral protein (ZAP) is a host factor that restricts the infection of many viruses mainly through RNA degradation, translation inhibition and innate immune responses.
Hsin-Ping Chiu, Han Chiu, Chao-Fu Yang, Yi-Ling Lee, Feng‐Lan Chiu, H. Kuo, Ren-Jye Lin, Yi-Ling Lin   +7 more
semanticscholar   +1 more source

Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source

Strategi Pencegahan Japanese Encephalitis (JE) Melalui Vaksinasi pada Anak Usia Dini di Wilayah Endemis

Dharma
Japanese Encephalitis (JE) is an infectious disease of the central nervous system caused by the Japanese Encephalitis Virus (JEV), JEV is the main cause of viral encephalitis in Asia. This virus is transmitted by mosquitoes and is zoonotic.
Siti Naimah, Jennifa Jennifa
doaj   +1 more source