Results 41 to 50 of about 198,176 (262)

Dialyzer surface area is a significant predictor of mortality in patients on hemodialysis: a 3-year nationwide cohort study

Scientific Reports, 2021
A target Kt/V of > 1.4 and use of a high-flux dialyzer are recommended for patients on hemodialysis. However, there is little information on the relationship between the dialyzer surface area and mortality in these patients.
Masanori Abe, Ikuto Masakane, Atsushi Wada, Shigeru Nakai, Kosaku Nitta, Hidetomo Nakamoto   +5 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Japanese Guideline for Childhood Asthma 2014

Allergology International, 2014
The Japanese Guideline for the Diagnosis and Treatment of Allergic Diseases 2013 (JAGL 2013) describes childhood asthma after the Japanese Pediatric Guideline for the Treatment and Management of Asthma 2012 (JPGL 2012) by the Japanese Society of ...
Yuhei Hamasaki, Yoichi Kohno, Motohiro Ebisawa, Naomi Kondo, Sankei Nishima, Toshiyuki Nishimuta, Akihiro Morikawa   +6 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Nationwide system to centralize decisions around ECMO use for severe COVID-19 pneumonia in Japan (Special Correspondence)

Journal of Intensive Care, 2020
The novel coronavirus disease 2019 (COVID-19) is spreading in Japan. We have collected a total of 26 patients with COVID-19 who required extracorporeal membranous oxygenation (ECMO). The available data from the first 14 cases demonstrated that the median
Japan ECMsOnet for COVID-19
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Empowering Junior Residents Aspiring to General Medicine: Lessons from HRC47, a Society-based Co-creation Model Led by Young Society Members

Journal of Hospital General Medicine
Since General Medicine (GM) was designated as a basic specialty in Japan in 2018, awareness of the field has increased, yet many junior residents interested in GM still face uncertainty due to limited information, unclear career pathways, and lack of ...
Maaya Fushie, Yuki Otsuka, Kosuke Ishizuka, Taiju Miyagami, Yohei Kanzawa, Yuko Ishise, Masayuki Amano, Kensuke Sugita, Sora Matsuda, Ryuto Watarai, Kyo Furuta, Wataru Kaita, Aiko Harada, Nozomi Aoki, Yukinori Harada, Taro Shimizu, Toshio Naito   +16 more
doaj   +1 more source

Policy for developing clinical practice guidelines of Japanese Society for Dialysis Therapy

Renal Replacement Therapy, 2017
Background The Scientific Academy Committee of Japanese Society for Dialysis Therapy (JSDT) has developed 14 clinical practice guidelines (CPGs) and their revised editions independently or in cooperation with other organizations and translated many of ...
Kosaku Nitta, Ikuto Masakane, Tadashi Tomo, Kenji Tsuchida, Kiyoshi Ikeda, Tomonari Ogawa, Eiichiro Kanda, Yoshihiko Kanno, Yasuhiro Komatsu, Masatomo Taniguchi, Fumika Taki, Takeshi Hasegawa, Norio Hanafusa, Takayuki Hamano, Masafumi Fukagawa, Jun Minakuchi, Hiroyasu Yamamoto, Naoki Washida, Takashi Wada, Yuzo Watanabe, on behalf of the Scientific Academy Committee of Japanese Society for Dialysis Therapy (JSDT)   +20 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Risk calculator for predicting postoperative pneumonia after gastroenterological surgery based on a national Japanese database

Annals of Gastroenterological Surgery, 2019
Background The aim of the present study was to develop a risk calculator predictive of postoperative pneumonia in patients undergoing gastroenterological surgery.
Yoshio Takesue, Hiroaki Miyata, Mitsukazu Gotoh, Go Wakabayashi, Hiroyuki Konno, Masaki Mori, Hiraku Kumamaru, Takashi Ueda, Kazuhiko Nakajima, Motoi Uchino, Yasuyuki Seto   +10 more
doaj   +1 more source