Results 51 to 60 of about 1,022,723 (297)

Medicine at mass gatherings: current progress of preparedness of emergency medical services and disaster medical response during 2020 Tokyo Olympic and Paralympic Games from the perspective of the Academic Consortium (AC2020)

open access: yesAcute Medicine & Surgery, 2021
Mass gatherings are events characterized by “the concentration of people at a specific location for a specific purpose over a set period of time that have the potential to strain the planning and response resources of the host country or community ...
Naoto Morimura   +58 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Policy for developing clinical practice guidelines of Japanese Society for Dialysis Therapy

open access: yesRenal Replacement Therapy, 2017
Background The Scientific Academy Committee of Japanese Society for Dialysis Therapy (JSDT) has developed 14 clinical practice guidelines (CPGs) and their revised editions independently or in cooperation with other organizations and translated many of ...
Kosaku Nitta   +20 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Risk calculator for predicting postoperative pneumonia after gastroenterological surgery based on a national Japanese database

open access: yesAnnals of Gastroenterological Surgery, 2019
Background The aim of the present study was to develop a risk calculator predictive of postoperative pneumonia in patients undergoing gastroenterological surgery.
Yoshio Takesue   +10 more
doaj   +1 more source

Nationwide system to centralize decisions around ECMO use for severe COVID-19 pneumonia in Japan (Special Correspondence)

open access: yesJournal of Intensive Care, 2020
The novel coronavirus disease 2019 (COVID-19) is spreading in Japan. We have collected a total of 26 patients with COVID-19 who required extracorporeal membranous oxygenation (ECMO). The available data from the first 14 cases demonstrated that the median
Japan ECMsOnet for COVID-19
doaj   +1 more source

High-performance dialyzers and mortality in maintenance hemodialysis patients

open access: yesScientific Reports, 2021
Few data are available regarding the association of dialyzer type with prognosis. In Japan, dialyzers are classified as types I, II, III, IV, and V based on β2-microglobulin clearance rates of 
Masanori Abe   +6 more
doaj   +1 more source

Costs in English and Japanese legal procedure [PDF]

open access: yes, 1998
The authors suggest that Japan is a non-litigious society because of high litigation costs and lengthy procedures and explain the system of costs and changes that have been made and consider what still needs to be done.
Jarman, Sam, Niiya, Satoko
core  

Japanese Ways of Addressing People [PDF]

open access: yes, 2002
This paper presents some Japanese forms of address. The use of correct forms of address in Japanese requires linguistic as well as social knowledge. Japanese people seem to avoid employing pronouns as address forms, employing other nouns instead.
Mogi, Norie
core   +2 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

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