Results 61 to 70 of about 1,022,723 (297)

Efficacy and continuability of 675 mg fremanezumab administration over 2 years

open access: yesThe Journal of Headache and Pain
Background Real-world data on the long-term adherence to- and efficacy of fremanezumab 675 mg quarterly dosing remain scarce. Our study evaluated the efficacy of- and patient adherence to 675 mg fremanezumab for episodic migraine (EM) and chronic ...
Shohei Yoshida   +8 more
doaj   +1 more source

Revolution or Evolution: The Transformation of Japanese Personnel Practices [PDF]

open access: yes, 1991
[Excerpt] Ever since Japan reemerged as an economic power from the ruins of the World War II, it is striking how the pace and magnitude of economic and social changes facing the country continue to increase.
Pucik, Vladimir
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

ニッケイ サンセイ ノ アイデンティティ ト セクシュアリティ ニッケイ シジン デヴィット ムラ ノ バアイ [PDF]

open access: yes, 2004
David Mura, who is a poet and the third generation of Japanese Americans, published several essays including Turning Japanese and Where the Body Meets Memory. In these books, he refers to some issues in his life: (1) his identity as a Japanese American, (
佐藤 清人
core   +1 more source

Policy Implications of Social Capital for the Japanese Social Security System [PDF]

open access: yes, 2008
We discuss the concept of social capital, which has received much attention recently. Social capital is important for the following 2 key reasons:(1) a highly democratic polity and a strong economic performance that attaches great importance to the ...
Hamada, Jun, Takao, Soshi
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Impact of adherence to board‐certified surgeon systems and clinical practice guidelines on colon cancer surgical outcomes in Japan: A questionnaire survey of the National Clinical Database

open access: yesAnnals of Gastroenterological Surgery, 2020
Aim To investigate the effectiveness of the institutional medical structure and of the implemented clinical practice guidelines for improving colon cancer surgical outcomes.
Hirotoshi Kobayashi   +8 more
doaj   +1 more source

Social Integration and Suicide Rates in Japan: An Analysis [PDF]

open access: yes, 2018
Japan has seen extreme changes in its social structures since the end of the 1800s. Before 1868, Japan practiced an exclusionary foreign policy known as sakoku (Japanese for “seclusion”), keeping Western influence out of the country for hundreds of years
Haley, Emily
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Heritage Language and L2 Learning Connections: Views from within Japan [PDF]

open access: yes, 2017
Bearing in mind the Japanese context, this paper elaborates on how maintenance of international children’s heritage language (HL) might contribute to the spread of bilingualism in the country.
Karsten, Angela   +3 more
core  

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