Results 61 to 70 of about 131,464 (268)
Clinical Outcomes of CAD-CAM Subperiosteal Implants for the Rehabilitation of Atrophic Jaws
Dentistry JournalThanks to the use of new digital technologies and innovations in materials, there has been an increasing interest in subperiosteal implants. These implants are considered to be helpful for the rehabilitation of severe jaw atrophies, as they overcome some
Giulio Gasparini +11 more
doaj +1 more source
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
Advanced Science, EarlyView.In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Advanced Science, EarlyView.Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
A Portable and Dual‐Button Microneedle Device Enables Intelligent Multimodal Laser Sensing
Advanced Science, EarlyView.A portable and dual‐button microneedle device enables rapid interstitial fluid sampling. Coupled with multimodal laser sensing and AI‐assisted data processing, the platform enables simultaneous molecular and elemental analysis for minimally invasive and multiplexed health assessment toward point‐of‐care diagnostics.
Yuanchao Liu +12 more
wiley +1 more source
Advanced Science, EarlyView.This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng +10 more
wiley +1 more source
Brazilian Journal of Biology, 2009 The aim of this study was to study the sexual dimorphism in adult Chaetophractus villosus (Desmarest, 1804), from northern Patagonia, Argentina. Eight mandibular traits were measured in 37 males and 34 females.
SM. Squarcia +3 more
doaj +1 more source
CCL3 and IL‐7 Synergistically Enhance CAR‐T Efficacy in Solid Tumors
Advanced Science, EarlyView.Synergistic delivery of CCL3 and IL‐7 by CAR‐T cells overcomes the immunosuppressive tumor microenvironment by enhancing cell infiltration, survival, and local immune reprogramming. This also establishes positive feedback that amplifies anti‐tumor activity and memory responses in both CAR‐T and endogenous T cells, presenting a robust therapeutic ...
Huanpeng Chen +12 more
wiley +1 more source
Intraosseous Inflammatory Myofibroblastic Tumor of the Posterior Mandible: A Rare Case with Immunohistochemical Interpretation [PDF]
Journal of DentistryInflammatory myofibroblastic tumor (IMT), previously called an inflammatory pseudotumor, is an unusual, rare, benign, but aggressive tumor of soft tissue origin.
Vandana Tripathi +3 more
doaj +1 more source