Results 31 to 40 of about 51,603 (263)

Diseases of the Jaws [PDF]

open access: yesThe Boston Medical and Surgical Journal
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openaire   +1 more source

Engagement Patterns With an Artificial Intelligence Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah   +4 more
wiley   +1 more source

Mechanisms of the trigeminal-lateral parabrachial-rostroventral medullary circuits involved in experimental occlusal interference induced chronic orofacial pain

open access: yesThe Journal of Headache and Pain
Background Chronic orofacial pain is a prevalent and debilitating condition, with complex bidirectional interactions between sensory and emotional processing.
Siyi Mo   +8 more
doaj   +1 more source

Strong‐Magnetic Flexible Composites for Magnetically Responsive Soft Robots

open access: yesAdvanced Robotics Research, EarlyView.
This perspective provides an overview of the performance mechanisms, preparation methods, and applications of strong magnetic flexible composite materials in soft actuators (such as gripping, movement, and sensing), and further explores current opportunities and challenges.
Wenwen Li   +4 more
wiley   +1 more source

Exploring the relationship between muscle activity, jaw behaviour and pain

open access: yesScientific Reports
While muscle overload is commonly implicated in musculoskeletal pain conditions, real-time assessment of associated behavioural and physiological features is challenging. This study aims to investigate the relationship between self-reported awake bruxism
Nikola Stanisic   +7 more
doaj   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

open access: yesAdvanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong   +14 more
wiley   +1 more source

Biomechanical behavior of customized scaffolds: A three-dimensional finite element analysis

open access: yesMaterials & Design, 2022
Teeth loss due to periodontal diseases, trauma, or infections often causes dimensional loss in the affected maxillary. In patients with reduced maxillary size, restoration of chewing function and esthetics with endosseous dental implants may fail.
Jessica León de Ulloa   +5 more
doaj   +1 more source

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

open access: yesAdvanced Science, EarlyView.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha   +5 more
wiley   +1 more source

Role of hormones in bone remodeling in the craniofacial complex: A review

open access: yesJournal of Oral Biology and Craniofacial Research, 2023
Background: Diseases such as periodontitis and osteoporosis are expected to rise tremendously by 2050. Bone formation and remodeling are complex processes that are disturbed in a variety of diseases influenced by various hormones.
Erin Grinde Tunheim   +2 more
doaj   +1 more source

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao   +14 more
wiley   +1 more source

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