Results 81 to 90 of about 118,059 (335)

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Involvement of the mouth and jaw area in dermatological diseases

GMS Hygiene and Infection Control
Background: The oral cavity can be affected by a variety of disorders, and many systemic disorders have wide range of manifestations in the oral cavity. Oral mucosal lesions can be early manifestations of the disease or the only symptom of dermatological
Ramiah, Vasudevi, Sankar, Shenbaga Lalitha, Shunmugavelu, Karthik, Hussain, Sajid Tajamul, Sadasivam, Manju Palanisamy, Behura, Shyam Sundar   +5 more
doaj   +1 more source

Congenital Adrenal Hyperplasia: A Case Report with Premature Teeth Exfoliation and Bone Resorption [PDF]

, 2015
Congenital adrenal hyperplasia (CAH) is an inherited autosomal recessive disorder characterized by insufficient production of cortisol. The aim of this case report was to present a child with CAH, premature exfoliation of primary teeth and accelerated ...
Angelopoulou, Matina V., Emmanouil, Dimitris E., Kontogiorgos, Elias D.   +2 more
core   +1 more source

A review on the prevention of inflammatory periimplant diseases [PDF]

, 2019
Background: An impressive number of dental implants are inserted worldwide. Evolution in dental implants and simplification of surgical techniques allowed a significant increase in the number of dentists involved in implant surgery.
Di Nardo, D., Passariello, C., Polimeni, A., Testarelli, L.   +3 more
core   +1 more source

Lip and Jaw Tremor in Parkinson’s Disease

Tremor and Other Hyperkinetic Movements
Parkinson's disease (PD) is characterized clinically by the presence of bradykinesia, rigidity, and tremor. Although upper limb rest tremor is the most common form of tremor in PD, lip/jaw tremor is identified in a proportion of these patients.We aimed to assess the frequency, features, and correlates of lip/jaw tremor in PD.We studied 229 consecutive ...
José Fidel Baizabal-Carvallo, Marlene Alonso-Juarez, Robert Fekete   +2 more
openaire   +2 more sources

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

Central Sensitization in the Bladder Pain Syndrome [PDF]

, 2016
Introduction: Nociceptive hyper-excitability and Central Sensitization (CS), have been identified as responsible for maintaining pain in several chronic neuropathic pain conditions, among which Bladder pain syndrome (BPS). Aim of the present study was to
Cambieri, Chiara, Ceccanti, Marco, Cervigni, M, Gori, Mc, Inghilleri, Maurizio, Nasta, L, Onesti, Emanuela   +6 more
core  

Molecular events in the jaw vascular unit: A traditional review of the mechanisms involved in inflammatory jaw bone diseases [PDF]

, 2023
Ruyu Wang, Haoran Wang, Junyu Mu, Hua Yuan, Yongchu Pang, Yuli Wang, Yifei Du, Han Feng   +7 more
openalex   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

Advanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin, Supawadee Jariyasakulroj, Yang Shu, Jingyi Chen, Qing Chang, Pao‐Fen Ko, Yuyueyang Qiu, Feixiang Chen, David Ahn, Zhen Zhao, Jian‐Fu Chen   +10 more
wiley   +1 more source

Transcutaneous oximetry of angiosomes of maxillary and facial arteries

Сучасні медичні технології
Aim. To qualitatively predict and control the quality of periodontal diseases treatment, to determine changes in the transcutaneous pressure of oxygen and carbon dioxide in angiosomes of maxillary and facial arteries in healthy adults.
I. I. Luchyn, A. V. Kryvanych, N. I. Zhero, F. M. Pavuk, V. I. Rusyn   +4 more
doaj   +1 more source