Results 331 to 340 of about 2,027,813 (387)

The Spleen Promotes Liver Sinusoidal Endothelial Cell Angiogenesis by Stimulating the TGFβ/Smad2/3 Pathway Through GDF15

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aims Liver sinusoidal endothelial cells (LSECs) are crucial nonparenchymal cells involved in liver fibrosis progression. Liver fibrosis develops from various chronic liver diseases, with pathological progression associated with the spleen. However, the precise mechanism by which the spleen influences LSECs during fibrosis is not
Xi Deng   +9 more
wiley   +1 more source

The Number of Newly Dispensed Hypnotic Drugs During the First COVID‐19 Lockdown Period in The Netherlands

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT The 2019 coronavirus (COVID‐19) pandemic and associated lockdowns significantly disrupted healthcare systems, including access to pharmacological treatments such as sleep medication. This study investigated the number of first‐time dispensed hypnotic drugs during the first COVID‐19 lockdown in the Netherlands, using data from the Dutch ...
Dana M. Dijkgraaf   +5 more
wiley   +1 more source

High‐Efficiency and Eco‐Friendly Management of Multiple Fungal Diseases by a Novel Carbon Dots sCDP Delivered RNA Nano‐Pesticides

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT RNA‐based pesticides represent a transformative approach in agricultural disease management, offering an environmentally sustainable alternative to conventional chemical fungicides. However, key challenges such as rapid RNA degradation in the environment and inefficient uptake hinder widespread adoption.
Chunhao Jiang   +10 more
wiley   +1 more source

ZmTH1 Is Vital for Healthy Plant Growth and Promotes Cold/Drought Tolerance by Regulating Thiamin Diphosphate‐Dependent Metabolisms in Maize

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Vitamin B1 (VB1) plays a crucial role in sustaining plant health and enabling adaptive responses to environmental stress. The complex maize genome implies a sophisticated VB1 synthesis pathway, with the mechanisms by which VB1 benefits plants remaining elusive.
Tengfei Zhang   +8 more
wiley   +1 more source

The TaMADS2‐TaTBL21 Module Enhances Wheat Resistance to Stripe Rust by Activating TaGKL‐Mediated Immunity

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Wheat stripe rust (Puccinia striiformis f. sp. tritici, Pst) poses a catastrophic threat to global food security. While MADS‐box transcription factors regulate development and abiotic stress, their roles in plant‐pathogen immunity remain enigmatic.
Shijia Zhao   +14 more
wiley   +1 more source

Two Highly Efficient Prime Editing Systems Based on the Csy4 CRISPR Endonuclease

open access: yes
Plant Biotechnology Journal, EarlyView.
Yu Lu   +12 more
wiley   +1 more source

Detection of JC Virus in the Brains of Korean Glioblastoma Multiforme Patients.

open access: green, 2004
한종완   +5 more
openalex   +1 more source

Revisiting JC virus and progressive multifocal leukoencephalopathy

Journal of NeuroVirology, 2023
Since its definition 65 years ago, progressive multifocal leukoencephalopathy (PML) has continued to devastate a growing population of immunosuppressed patients despite major advances in our understanding of the causative JC virus (JCV). Unless contained by the immune system, JCV lyses host oligodendrocytes collateral to its life cycle, leading to ...
Angela Rocchi   +2 more
semanticscholar   +3 more sources

Clinicopathologic Characteristics of JC Virus Nephropathy in Kidney Transplant Recipients.

Transplantation, 2020
BACKGROUND The vast majority of polyomavirus nephropathy (PVN) are due to BK virus, but rare cases result from JC virus reactivation. To date, only a handful of biopsy-proven JC-PVN cases have been reported.
Nasim Wiegley   +6 more
semanticscholar   +1 more source

JC virus‐associated nephropathy in a post‐heart and ‐kidney transplantation patient

Transplant Infectious Disease, 2020
JC virus‐associated nephropathy is rare in kidney transplant recipients, and even rarer in recipients of other solid organ transplants. We present a case of JC virus‐associated nephropathy in a heart‐kidney transplant recipient, which to our knowledge is
J. Aguilar   +7 more
semanticscholar   +1 more source

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