Recurrent Mutations of the Active Adenylation Domain of UBA1 in Atypical Form of VEXAS Syndrome [PDF]
HemaSphere, Volume 7, Issue 4, April 2023.
Alyx Faurel +12 more
doaj +3 more sources
Pour le commentaire du Libre dels Grands jorns de Jean Boudou : quatre notes [PDF]
1. La double structuration du libre dels Grands jorns La question de la structure narrative des Grands jours n’a guere ete abordee par la critique. Les lignes qu’on va lire voudraient contribuer a la discussion a ce sujet. 1.1. Aucun lecteur du libre dels Grands jorns ne peut demeurer insensible aux deux correlations suivantes qui s’etablissent entre ...
Jean-Pierre Chambon
doaj +2 more sources
Force propagation between epithelial cells depends on active coupling and mechano-structural polarization [PDF]
Cell-generated forces play a major role in coordinating the large-scale behavior of cell assemblies, in particular during development, wound healing, and cancer.
Artur Ruppel +12 more
doaj +2 more sources
Burden of grade 3 or 4 liver injury associated with immune checkpoint inhibitors [PDF]
Background & Aims: There is concern about the burden of liver injury in patients with cancer exposed to immune checkpoints inhibitors (ICIs). Methods: In a retrospective cohort study, we evaluated the likelihood of grade 3/4 liver injury, of grade 3 ...
Lucia Parlati +37 more
doaj +2 more sources
Management and outcomes of adolescent and young adult sarcoma patients: results from the French nationwide database NETSARC [PDF]
Background The initial management of patients with sarcoma is a critical issue. We used the nationwide French National Cancer Institute-funded prospective sarcoma database NETSARC to report the management and oncologic outcomes in adolescents and young ...
Pierre Kubicek +49 more
doaj +2 more sources
Effects of the 2018 European summer heatwave on the incidence of sporadic bacterial gastroenteritis in a temperate maritime climate region (Republic of Ireland) [PDF]
Background: The IPCC recognises that climate change and associated extreme weather events (EWEs), including heatwaves, will incur negative human health impacts.
Martin Boudou +5 more
doaj +2 more sources
Breakpoint modelling of temporal associations between non-pharmaceutical interventions and symptomatic COVID-19 incidence in the Republic of Ireland. [PDF]
BackgroundTo constrain propagation and mitigate the burden of COVID-19, most countries initiated and continue to implement several non-pharmaceutical interventions (NPIs), including national and regional lockdowns.
Martin Boudou +4 more
doaj +2 more sources
Development and validation of a host-dependent, PDL1-independent, biomarker to predict 6-month progression-free survival in metastatic non-small cell lung cancer (mNSCLC) patients treated with anti-PD1 immune checkpoint inhibitors (ICI) in the CERTIM Cohort: The ELY study [PDF]
Background: Immune checkpoint inhibitors (ICI) are dramatically active in a minority of non-small cell lung cancer (NSCLC) patients. We studied here the relationship between patients's metabolism and outcome under ICI.
Pascaline Boudou-Rouquette +17 more
doaj +2 more sources
Chemical and Enzymatic Probing of Viral RNAs: From Infancy to Maturity and Beyond [PDF]
RNA molecules are key players in a variety of biological events, and this is particularly true for viral RNAs. To better understand the replication of those pathogens and try to block them, special attention has been paid to the structure of their RNAs ...
Orian Gilmer +5 more
doaj +2 more sources
Maladies de la fin : La Santa Estela del Centenari et Lo Libre dels grands jorns de Jean Boudou
La mort de la langue est partout dans la litterature occitane. Elle hante les esprits d'un nombre considerable d'ecrivains. Certains accordent a cette peur une place preponderante, en font un element moteur de leur creation comme Jean Boudou. L'analyse de l'A. porte sur deux romans, "La Santa Estale del Centenari" et "Lo Libre dels grands jorns".
Catherine Parayre
doaj +2 more sources

