Results 71 to 80 of about 326,293 (219)

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

open access: yesiMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu   +8 more
wiley   +1 more source

Adenokarcinom crijeva kod smeđeg medvjeda (Ursus arctos) - prikaz slučaja [PDF]

open access: yes, 2018
This article presents the first case of intestinal adenocarcinoma in a free living, culled 12 year old, European female brown bear (Ursus arctos), with its characteristic macropathological and histopathological manifestations.
Andrea Gudan Kurilj   +8 more
core   +2 more sources

Gastrointestinal stromal tumor: case report

open access: yesArchivo Médico de Camagüey, 2018
Background: the gastrointestinal stromal tumors, are mesenchymal tumors that appear in any place of gastrointestinal tract. Many of them can be pediculate and difficult pre-operatory diagnosis.
Yon Luis Trujillo-Pérez   +4 more
doaj  

Giant jejunal leiomyosarcoma: a rare case

open access: yesInternational Surgery Journal, 2018
Unlike other gastrointestinal neoplasms, small bowel tumours are often rare. Of this, leimyosarcoma of jejnum is extremely uncommon. Most of these patients are asymptomatic however in few cases may present with acute presentation such as intestinal ...
J. Srikanth   +3 more
semanticscholar   +1 more source

Case Series: Natural History and Treatment of Thoracic Aortic Sarcoma

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Aortic sarcoma is a rare and aggressive malignancy with a poor prognosis despite surgical resection and vascular reconstruction. We present a case series of patients with thoracic aortic sarcoma, highlighting three distinct clinical scenarios: primary resection, resection following prior thoracic aortic endograft, and nonoperative management ...
Calvin L. Chao   +2 more
wiley   +1 more source

Clinics in diagnostic imaging. 159. Jejunal intussusception due to Peutz-Jeghers syndrome.

open access: yesSingapore medical journal, 2015
A 21-year-old woman presented with acute onset of upper abdominal pain. A diagnosis of Peutz-Jeghers syndrome (PJS) was made based on the clinical picture of perioral pigmentation with imaging findings of transient jejunojejunal intussusceptions and ...
V. Krishnan, A. Chawla, E. Wee, W. Peh
semanticscholar   +1 more source

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

open access: yesSmall Methods, EarlyView.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai   +9 more
wiley   +1 more source

Surgical strategies for duodenal GISTs: benefits and limitations of minimal resections [PDF]

open access: yes, 2015
Comment on Conservative surgery vs. duodeneopancreatectomy in primary duodenal gastrointestinal stromal tumors (GIST): a retrospective review of 114 patients from the French sarcoma group (FSG).
Balducci, Genoveffa   +5 more
core   +1 more source

European Consensus on Malabsorption—UEG & SIGE, LGA, SPG, SRGH, CGS, ESPCG, EAGEN, ESPEN, and ESPGHAN

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Malabsorption is a complex and multifaceted condition characterised by the defective passage of nutrients into the blood and lymphatic streams. Several congenital or acquired disorders may cause either selective or global malabsorption in both children and adults, such as cystic fibrosis, exocrine pancreatic insufficiency (EPI), coeliac ...
Marco Vincenzo Lenti   +29 more
wiley   +1 more source

Radiological evaluation of esophageal function in dysphagia with special emphasis on achalasia [PDF]

open access: yes, 2008
In idiopathic achalasia, degeneration of the inhibitory innervation of the esophageal smooth muscle results in absence of primary peristalsis and in incomplete relaxation of the lower esophageal sphincter (LES).
Andersson, Mats
core  

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