Results 61 to 70 of about 119,314 (303)
Clinical Pharmacology &Therapeutics, EarlyView.Accurate prediction of oral drug absorption in humans is essential for early drug development; however, physiologically relevant human models are lacking. This study aims to comprehensively assess the EpiIntestinal™, a human primary intestinal 3D model, for its ability to predict oral absorption (Fa), intestinal availability (Fg), CYP3A4 induction, and
Paresh P. Chothe +4 more
wiley +1 more source
Chemical Impacts of the Microbiome Across Scales Reveal Novel Conjugated Bile Acids [PDF]
, 2019 A mosaic of cross-phyla chemical interactions occurs between all metazoans and their microbiomes. In humans, the gut harbors the heaviest microbial load, but many organs, particularly those with a mucosal surface, associate with highly adapted and ...
Mazmanian, Sarkis +2 more
core
Gastrointestinal stromal tumor (GIST) of the Treitz’s angle– a very rare cause of high bowel obstruction [PDF]
, 2016 Gastrointestinal stromal tumors (GIST) are somewhat rare gastrointestinal tumors - approximately 1% to 3% incidence, but they are the most common mesenchymal neoplasms of the gastrointestinal tract.
Georgescu, Lota Corina +3 more
core +3 more sources
Uric Acid‐Lowering and Anti‐Hyperuricemia Effects of Plant‐Based Nutraceuticals and Foods: A Review
Food Chemistry International, EarlyView.Increased UA production and/or decreased UA secretion cause hyperuricemia. Effects and mechanism of flavonoids in reducing UA are summarized. Terpenoids, saponins, alkaloids, vitamin C, polysaccharides, peptides are effective. Plant‐based foods with UA‐lowering ability are reviewed.
Linwei He, Wenjian Yang, Jianhui Liu
wiley +1 more source
Intestinal Electric Stimulation Accelerates Whole Gut Transit and Promotes Fat Excrement in Conscious Rats [PDF]
, 2009 *_Introduction:_* Intestinal electric stimulation (IES) is proposed as a potential tool for the treatment of morbid obesity. Our previous study showed that IES with one pair of electrodes accelerated intestinal transit and decreased fat absorption in a ...
Jiande Chen, Ying Sun
core +2 more sources
Food Frontiers, EarlyView.Our results indicate that maternal ISO‐S during late gestation and throughout lactation can improve offspring intestinal homeostasis, which may be related to antioxidant enzymes and immunoglobulins in sow colostrum through maternal metabolome–microbiome intestine interactions.
Changming Hong +9 more
wiley +1 more source
Cadaveric small bowel and small bowel-liver transplantation in humans [PDF]
, 1992 Five patients had complete cadaveric small bowel transplants under FK506 immunosuppression, one as an isolated graft and the other 4 in continuity with a liver. Three were children and two were adults.
Abu-Elmagd, K +13 more
core +1 more source
Food Biomacromolecules, EarlyView.Abstract Metabolic syndrome (MetS) is a complex noncommunicable condition characterized by central obesity, insulin resistance, hyperlipidemia, hypertension, and hyperglycemia. Epidemiological evidence shows that MetS affects a third of the global population; however, due to its complex pathogenesis and limited drug therapy options, the increasing ...
Josiah Owuor Oyalo +3 more
wiley +1 more source
Effects of Single-Dose Prucalopride on Intestinal Hypomotility in Horses: Preliminary Observations [PDF]
, 2017 Abnormalities of gastrointestinal motility are often a challenge in horses; however, the use of prokinetic drugs in such conditions must be firmly established yet.
Bassotti, G. +7 more
core +2 more sources
Food Safety and Health, EarlyView.This review focuses on the potential of sub‐Saharan African fermented food products as sources of probiotic yeasts for improved food security and health. ABSTRACT Research on probiotic yeasts from fermented products in sub‐Saharan Africa was limited in the past, but there is currently a surge in investigative efforts in this field.
Lethiwe Lynett Mbuyane
wiley +1 more source