Results 71 to 80 of about 126,105 (358)

An Effective Oral Drug Delivery Route for Pharmacokinetic Complications: Spirulina Lipid Nanotechnology System

open access: yesAdvanced Science, EarlyView.
Spirulina‐nano system facilitates the formation of drug coating on spirulina's surface through electrostatic adsorption. It targets intestinal villi effectively and overcomes the pharmacokinetic complications of IBS‐D. This system successfully carried out the treatment of multiple symptoms, including diarrhea, visceral hypersensitivity, mental symptoms,
Jiahui Ye   +7 more
wiley   +1 more source

Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection. [PDF]

open access: yes, 2016
HIV targets the gut mucosa early in infection, causing immune and epithelial barrier dysfunction and disease progression. However, gut mucosal sensing and innate immune signaling through mucosal pattern recognition receptors (PRRs) during HIV infection ...
Bäumler, AJ   +9 more
core   +2 more sources

Tissular Genomic Responses to Oral FB1 Exposure in Pigs

open access: yesToxins, 2022
Fumonisin B1 (FB1) is a widespread mycotoxin produced by fungal Fusarium species—mainly in maize, one of the plants most commonly used for food and feed. Pigs and horses are the animal species most susceptible to this mycotoxin.
Léonie Dopavogui   +15 more
doaj   +1 more source

Photobiomodulation Strengthens Muscles via Its Dual Functions in Gut Microbiota

open access: yesAdvanced Science, EarlyView.
Non‐invasive photobiomodulation therapy (PBMT) enhances muscle endurance by rewiring the gut‐muscle axis. PBMT preserves gut epithelial integrity and enriches beneficial anaerobes, driving metabolites such as butyrate, spermidine, and L‐carnitine that supercharge mitochondrial energy in skeletal muscles.
Prabhat Upadhyay   +3 more
wiley   +1 more source

Changes in Tight Junction Protein Expression Levels but Not Distribution in Commercial White and Brown Laying Hens Supplemented with Chondrus crispus or Ascophyllum nodosum Seaweed

open access: yesAnimals
It is proposed that prebiotic diet supplements improve intestinal function, in part by improving the barrier function of the intestinal epithelium with an associated increase in the expression of tight junction proteins, including occludin and zonula ...
Leslie A. MacLaren   +3 more
doaj   +1 more source

Effects of Enterotoxigenic Escherichia coli Challenge on Jejunal Morphology and Microbial Community Profiles in Weaned Crossbred Piglets

open access: yesMicroorganisms, 2023
Pathogenic enterotoxigenic Escherichia coli (ETEC) is a major cause of bacterial diarrhea in weaning piglets, which are vulnerable to changes in environment and feed.
Juan Xu   +4 more
doaj   +1 more source

T‐2 Toxin Exploits Gut‐Derived Staphylococcus Saprophyticus to Disrupt Hepatic Macrophage Homeostasis

open access: yesAdvanced Science, EarlyView.
T‐2 toxin promotes the proliferation of intestinal S. saprophyticus and facilitates its translocation to the liver in piglets and mice. The translocated bacteria trigger autophagy in Kupffer cells and recruit monocytes to the liver through the nucleotide‐binding oligomerization domain 2 (NOD2) signaling pathway, alongside the M1 polarization of hepatic
Yuanyuan Zhu   +19 more
wiley   +1 more source

Unusual complication of a percutaneous gastrostomy tube

open access: yesJournal of Community Hospital Internal Medicine Perspectives, 2019
Percutaneous Gastrostomy (PEG) tube is an endoscopic-guided procedure to provide enteral nutrition, medications and/or fluids to patients with oral or esophageal pathologies.
Fahad Malik   +4 more
doaj   +1 more source

Neurofibroma of the appendix and multiple gastrointestinal stromal tumors of small bowel in neurofibromatosis type 1 patient [PDF]

open access: yesKorean Journal of Clinical Oncology, 2014
Neurofibromatosis type 1 (NF-1) is an autosomal dominant hereditary disease with association of tumorous condition of body. Although the pathogenesis of tumorous condition with NF-1 is unclear, there were several reports for gastrointestinal tumors ...
Gui-Ae Jeong
doaj   +1 more source

The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track

open access: yesAdvanced Science, EarlyView.
In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and
Chun Huang   +12 more
wiley   +1 more source

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